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Perioperative Use of Serum Creatinine and Postoperative Acute Kidney Injury

Perioperative Use of Serum Creatinine and Postoperative Acute Kidney Injury: an Observational, Monocentric, Retrospective Study to Explore Physicians' Perception and Practice.

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04341974
Acronym
CreaPeriop
Enrollment
423
Registered
2020-04-10
Start date
2019-01-01
Completion date
2020-03-31
Last updated
2020-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Surgery, Malignancy, Acute Kidney Injury, Cronich Kidney Disease

Keywords

serum creatinine, kidney dysfunction

Brief summary

The perioperative approach adopted in a cohort of adult oncological patients undergoing major abdominal surgery will be described. In particular, the physician's attitude toward use of sCr for identification of patients at risk for PO-AKI will be described, as well as the patients who should be reassessed in the long term for progression toward CKD. The incidence and risk factors associated with PO-AKI and renal function deterioration within a year postoperatively will be also evaluated.

Interventions

DIAGNOSTIC_TESTSerum creatinine

Will be described: 1) the number of patients actually screened with postoperative serum creatinine and 2) the number of patients actually screened with the same parameter at the long-term after surgery

Sponsors

Careggi Hospital
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Adult patients * Scheduled for elective surgery * Surgery for oncological disease

Exclusion criteria

* Patients undergoing postoperative chemotherapy * Patients who died within 12 month after surgery

Design outcomes

Primary

MeasureTime frameDescription
Adoption of serum creatinine as marker of acute kidney injury postoperively3rd postoperative dayNumber of actual patients screened postoperatively

Secondary

MeasureTime frameDescription
Incidence of acute kidney injury3rd postoperative dayNumber of patients with a postoperative diagnostic increase of serum creatinine, in accordance with KDIGO guidelines
Adoption of serum creatinine as marker of long term kidney dysfunction12 month after surgeryNumber of actual patients screened at the long term
Incidence of long term kidney dysfunction12 month after surgeryNumber of patients with a long term reduction in GFR greater than 10 ml/min with respect to the baseline

Countries

Italy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 22, 2026