Corona Virus Infection, Critically Ill, Pneumonia, Viral
Conditions
Keywords
COVID-19, SARS-Cov-2, Intensive Care Unit
Brief summary
Since December 2019, a new agent, the SARS-Cov-2 coronavirus has been rapidly spreading from China to other countries causing an international outbreak of respiratory illnesses named COVID-19. In France, the first cases have been reported at the end of January with more than 60000 cases reported since then. A significant proportion (20-30%) of hospitalized COVID-19 patients will be admitted to intensive care unit. However, few data are available for this special population in France. We conduct a large observational cohort of ICU suspected or proven COVID-19 patients that will enable to describe the initial management of COVID 19 patients admitted to ICU and to identify factors correlated to clinical outcome.
Interventions
OTHERNo intervention
No intervention
Sponsors
Centre Hospitalier Universitaire de Nīmes
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients admitted to ICU for suspected or proven SARS-Cov-2 infection, defined by positive SARS-Cov-2 PCR or CT scan images * Patient \> or= 18 years
Exclusion criteria
* Patient study refusal * Patient already enrolled in the present study * Patient with respiratory illness with negative COVID-19 CT scan images and negative COVID\_19 PCR
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Mortality at day 28 | day 28 | Mortality at day 28 |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Imaging | day 1 | Delay in imaging in hours |
| Delay in Microbiological diagnosis | day 1 | delay in microbiological diagnosis in hours |
| Antiviral therapy | up to day 28 | Antiviral therapy Yes / no |
| Antibiotic therapy | day 28 | Antibiotic therapy Yes / No |
| severe complications | up to day 28 | severe complications (pulmonary embolism, acute kidney injury, myocarditis, cardiac arrest, liver failure, ventilator associated pneumonia) Yes / No |
| Patients receiving renal replacement therapy | up to day 28 | number |
| Patients receiving mechanical ventilation | up to day 28 | number |
| Vital status | day 28 | Patient alive at day 28 : yes / No |
| Covid-19 treatments | up to day 28 | Covid-19 treatments Yes / No |
Countries
France
Outcome results
None listed