Vitamin D and Type 2 Diabetes Risk in UK Adults

Association Between Vitamin D Status and Risk of Type 2 Diabetes in a Population of UK Adults: A Cross-sectional Study.

Status

Suspended

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04339530

Enrollment

300

Registered

2020-04-09

Start date

2019-07-01

Completion date

2022-07-01

Last updated

2021-05-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity, Overweight

Keywords

Vitamin D, Type 2 diabetes, Insulin resistance, Glucose

Brief summary

This study is exploring the association between vitamin D and Type 2 diabetes risk in normal weight and overweight UK adults.

Detailed description

The aim of this study is to assess the link between vitamin D status and glucose homeostasis in a population of normal weight and overweight individuals (BMI\> 18.5 Kg/m2).

Interventions

OTHERNormal weight and overweight adults

Association between vitamin D levels and insulin resistance

Study design

Observational model

OTHER

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

18 Years to 50 Years

Healthy volunteers

Yes

Inclusion criteria

* Normal weight and overweight and obese adults (BMI\>= 18.5 Kg/m2) with no restriction to ethnicity, occupation or socioeconomic status. * Males and females * 18-50 years

Exclusion criteria

* Patients diagnosed with diabetes type 2, myocardial infarction or coronary heart disease. * HbA1c \> 6.4% * Pregnancy * Diagnosis of liver disease (including liver enzymes \> 3 times above normal values) * Diagnosis of renal disease (creatinine of \> 150 mmol/l) * Post-menopausal women

Design outcomes

Primary

Measure	Time frame	Description
HOMA-IR (Homeostasis modelling assessment-Insulin resistance)	One venous sample collected after 8 hours of fasting	A venous blood sample collected for the measurement of insulin and glucose levels.

Secondary

Measure	Time frame	Description
Fasting bood glucose levels	One venous sample collected after 8 hours of fasting	A venous blood sample collected for the measurement of glucose levels
HbA1C	Sample collected at one single time point with no follow-up	Fingerprick sample
Body fat percentage	Measurement conducted in the morning after 8 hours of fasting	Body fat percentage measured through DEXA
Central and brachial Systolic and Diastolic Blood pressure	Measurement taken 3 times after a-10 minute rest	Blood pressure measured using a digital sphygmomanometer
Augmentation index	Measurement taken 3 times after a-10 minute rest	Arterial stiffness assessment test

Countries

United Kingdom

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026