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Fertility in Untreated Rectosigmoid Endometriosis

Fertility in Patients With Untreated Rectosigmoid Endometriosis

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04338035
Enrollment
215
Registered
2020-04-08
Start date
2009-05-01
Completion date
2020-01-01
Last updated
2020-11-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Endometriosis, Bowel Endometriosis, Endometriosis, Rectum, Endometriosis Colon

Brief summary

Several studies investigated the reproductive outcomes after surgical treatment of colorectal endometriosis, mainly segmental colorectal resection. Little information is available on the spontaneous fertility of patients with bowel endometriosis. This study aims to evaluate the fertility of patients affected by rectosigmoid endometriosis who did not undergo previous surgical treatment.

Interventions

Patients did not undergo surgical treatment for endometriosis and medical consultations were done every 6 months from the beginning of the attempts to conceive

Sponsors

Ospedale Policlinico San Martino
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
FEMALE
Age
18 Years to No maximum

Inclusion criteria

* Desire of conception * Diagnosis of rectosigmoid endometriosis by transvaginal ultrasonography (TVS) and magnetic resonance imaging enema (MR-e)

Exclusion criteria

* Previous surgery for endometriosis * Diagnosis of hydrosalpinx at imaging * Previous conception * Abnormal semen parameters of male partners

Design outcomes

Primary

MeasureTime frameDescription
Clinical pregnancy rate4-9 weeks after conceptionUltrasonographic evidence of intrauterine gestational sac
Live birth rate22 weeks after conceptionComplete expulsion or extraction from a woman of a product of fertilization after 22 completed weeks of gestational age, which, after such separation, breathes or shows any other evidence of life

Secondary

MeasureTime frameDescription
Number (%) of patients conceiving spontaneously/by Assisted Reproductive TechnologyImmediately after diagnosis of clinical pregnancyModality of conception
Number (%) of patients undergoing vaginal delivery/delivering by cesarean section22-42 weeks after conceptionModality of delivery

Countries

Italy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026