IOP and Ocular Biometrics Changes After Phacoemulsification in Glaucoma Patients and Controls

Intraocular Pressure and Ocular Biometrics Changes After Phacoemulsification in Glaucomatous Patients and Age Matched Controls, Comparative Study

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04334473

Enrollment

Registered

2020-04-06

Start date

2019-09-20

Completion date

2020-04-01

Last updated

2020-04-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glaucoma, Cataract

Keywords

Ocular bio-metrics, Anterior chamber depth, UBM

Brief summary

Effect of phacoemulsification on intraocular pressure has been studied with variable results.Furthermore, effect of phacoemulsification on ocular biometrics including anterior chamber depth and angle opening distance has also been studied. In our study we aim at establishing a quantitative relationship between preoperative ocular biometrics and postoperative intraocular pressure change and comparing this relationship in glaucomatous and non-glaucomatous eyes.

Detailed description

All patients will have the anterior chamber angle assessed by indentation gonioscopy preoperatively. Anterior Chamber Depth & lens thickness will be measured by Optical Biometry (lenstar 900) as well as measurement of the angle & lens vault using the Ultrasound Biomicrosopy (UBM) before and 1 month after cataract surgery. IOP will be measured pre- & postoperatively on day 7 and 30. Possible Risk (s): Risks of surgery(hemorrhage, endophthalmitis), Risks for investigations: minimal risk of infection To minimize the risk of infection: adherence to pre-& intraoperative infection-control measures, postoperative UBM is to be done at 1 month.

Interventions

PROCEDUREphacoemulsification and Intraocular lens implantation

Standartd surgical procedure with small incision to remove catarct using ultrasound waves. it can be done by topica, local or general anaesthesia acoording to patients general fitness and preference.

DIAGNOSTIC_TESTUltrasound Biomicrosopy (UBM)

A diagnostic test using ultrasound waves to evaluate the anterior chamber depth, angle and lens vault.

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

BASIC_SCIENCE

Masking

NONE

Intervention model description

All participants are assigned to the same interventions. All will undergo pre- & postoperative assessment, cataract surgery.

Eligibility

Sex/Gender

ALL

Age

40 Years to 70 Years

Healthy volunteers

Inclusion criteria

* Age 40-70 years. * Glaucomtous and nonglaucomatous participants with visually significant cataracts. * Best-corrected visual acuity (BCVA) equal to or worse than 6/12. * patients candidates for standard cataract surgeries without adjunctive procedure (e.g., pupil stretching or iris hooks).

Exclusion criteria

* Major intraoperative or postoperative complications from cataract surgery * Peripheral anterior synechiae (PAS) detected by indentation gonioscopy. * Uveitis, severe retinal diseases, or congenital Anomalies. * History of ocular trauma or any intraocular Surgery. ocular trauma or any intraocular Surgery

Design outcomes

Primary

Measure	Time frame	Description
Intraocular pressure change	4 weeks	intraocular pressure measurement by Goldman's applanation tonometr
ocular bio-metrics change	4 weeks	anterior chamber angle angle opening distance and anterior chamber depth change

Secondary

Measure	Time frame	Description
Phacoemulsification as treatment to glaucoma	4 weeks	intraocular pressure decrease after surgery in glaucoma patients

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026