Outcome of Cataract Surgery With Uveitis

Outcome of Cataract Surgery in Patient With Uveitis

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04333069

Enrollment

Registered

2020-04-03

Start date

2020-04-10

Completion date

2022-12-20

Last updated

2020-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cataract; Complicata

Keywords

uveitis

Brief summary

Aim of the study is to evaluate outcome of cataract surgery in different types of uveitis as regarding best corrected visual acuity (BCVA) and rate of post operative complications.

Detailed description

Cataract is the main cause of reversible blindness in patients with uveitis. Cataract occurs in up to 50% to 70% of patients with uveitis. Preoperative complications, including anterior synechiae, posterior synechiae, and pupillary membrane formation, may increase surgical challenges. In addition, recurrent inflammation increases the incidence of postoperative complications and often affects the visual prognosis. In recent years, phacoemulsification with intra ocular lens (IOL)implantation has become the main surgical method for treating uveitis (complicated cataract), and the visual prognosis of patients who undergo this procedure is usually favorable. Surgical treatment may be effective but is associated with higher rates of complication than in non uveitic eyes. Cystoid macular edema (CME) is the most common complication cataract surgery in the general population. Although, in most cases, the macular edema is self-limited, in rare cases it can lead to long-term visual deterioration that is difficult to treat. Another common complication after cataract surgery is posterior capsule opacification (PCO) , leading to symptoms of glare or blurred vision, reduced visual acuity, or impaired posterior segment exam. Factors that are critical in the development of PCO include surgical technique, type of implanted intra ocular lens (IOL) either foldable hydrophilic acrylic, hydrophobic acrylic or silicone and postoperative control of uveitis

Interventions

PROCEDUREcataract surgery

cataract surgery in form of phaco emulsification or irrigation aspiration

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

SCREENING

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

16 Years to 80 Years

Healthy volunteers

Inclusion criteria

\- Visually significant cataract ( means opacification of the crystalline lens adequate to interfere with vision)in patients with uveitis controlled for at least 1month.

Exclusion criteria

* Irreversible pathology affecting outcome e.g. macular scar ,optic atrophy, and retinal detachment. * Patients with active uveitis (means inflammation inside the eye). * Patients less than 16 years old.

Design outcomes

Primary

Measure	Time frame	Description
final postoperative uncorrected visual acuity (UCVA)	1 week post operative	post operative uncorrected visual acuity which mean visual acuity without spectacle correction
Final post operative best corrected visual acuity (BCVA)	1 week post operative	Post operative visual acuity with spectacle correction

Secondary

Measure	Time frame	Description
incidence of postoperative complications	6 months post operative	cystoid macular edema which mean inflammation, swelling and collection of fluid inside macula) .
Reactivation of intraocular inflammation	6 months post operative	Appearance of inflammatory activity inside the eye after period of quiescence of at least 6 months

Contacts

Primary ContactMona Abdallah Abd AlRazik Ahmed, MD

monaabdallah51290@aun.edu.eg01014398129

Backup ContactMohammed Gamal Saleh, lecturer

mgsaleh05@yahoo.com01004530716

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026