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Abortion-related Morbidity and Mortality in Conflict-affected and Fragile Settings Study

AMoCo Study: Abortion-related Morbidity and Mortality in Conflict-affected and Fragile Settings Study

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04331847
Acronym
AMoCo
Enrollment
2500
Registered
2020-04-02
Start date
2019-09-03
Completion date
2021-12-31
Last updated
2021-10-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Abortion Complication

Keywords

Near-miss, Risks factors, Maternal health, Abortion, Maternal mortality

Brief summary

To describe and estimate the burden of abortion-related complications, particularly near-miss complications and deaths, and their associated factors among women presenting for abortion-related complications in health facilities supported by Médecins Sans Frontières (MSF) in African fragile and/or conflict-affected settings.

Detailed description

Multi-sites mixed-methods study with 4 components: 1. A quantitative observational descriptive study among women presenting for abortion-related complications to determine the frequency and severity of abortion-related complications including near-miss cases and death. Data will be collected through a medical records review and a quantitative survey among women presenting for abortion-related complications to determine the sociodemographic and clinical characteristics of the women with abortion-related complications, the type of abortion, the type and severity of complications and the clinical management received. It will also give insight into the characteristics of near-miss events following unsafe abortion. 2. A qualitative study about women's experiences associated with a near-miss event (and potentially life threatening): their pathway of access to care including their decision-making process, their own perceptions and opinions and other factors or conditions that might contribute to the near-miss event (in-depth face to face interviews). 3. A rapid health facility assessment with the health professional in charge of Post-Abortion Care will complement the assessment of the quality of management of complications 4. A Knowledge Attitudes, Practice and Behavior quantitative survey among health care providers involved in the management of abortion-related complications will identify provider-associated factors that may contribute to near-miss events.

Interventions

None listed

Sponsors

Ipas
CollaboratorOTHER
Guttmacher Institute
CollaboratorOTHER
Medecins Sans Frontieres, Netherlands
CollaboratorOTHER
Epicentre
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
FEMALE
Healthy volunteers
No

Inclusion criteria

MEDICAL RECORD REVIEW: Inclusion Criteria: Women * with any signs or symptoms of abortion-related complications, i.e. any signs or symptoms of complications of spontaneous or induced abortion, whatever the abortion stage: inevitable, missed, incomplete, complete abortion . * Or with a presentation primary diagnosis of ectopic pregnancy or molar pregnancy

Exclusion criteria

* Threatened abortion (defined as vaginal bleeding with a closed cervix after having excluded the diagnosis of ectopic pregnancy or molar pregnancy) * History of abortion-related complications and presenting for an unrelated issue * Refusal to participate QUANTITATIVE INTERVIEW: Inclusion criteria: all women included in the medical record review subcomponent and hospitalized (who stayed overnight or more)

Design outcomes

Primary

MeasureTime frameDescription
From the Quantitative observational descriptive study:Between september 2019 and February 2021Proportion of near-miss cases among all women presenting for abortion-related complications.

Secondary

MeasureTime frameDescription
Quantitative observational descriptive study: medical record review+quantitative interviews:Between september 2019 and February 2021Facility-based abortion-related complications ratio per annum for the following denominators: live births, all admissions and deliveries
Qualitative study (qualitative in-depth interviews):Between september 2019 and February 2021Description of the woman pathway to care
Knowledge Attitude Practice and Behavior (KAPB) survey:Between september 2019 and February 2021Proportion of each knowledge, attitude and practice of health facility staff related to Post Abortion Care and Safe Abortion Care

Countries

Central African Republic, Democratic Republic of the Congo, Nigeria

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026