Platelet Rich Fibrin(PRF) Injection for Treatment of Dental Pulp Exposure:Randomized Clinical Trial

Platelet Rich Fibrin(PRF) Versus Pulp Capping in Treatment of Dental Pulp Exposure:Randomized Clinical Trial

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04330768

Enrollment

Registered

2020-04-01

Start date

2021-03-31

Completion date

2022-06-30

Last updated

2020-04-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dental Caries, Dental Pulp Exposure

Brief summary

platelet rich fibrin(PRF) obtained from patient from patient blood sample (before start of treatment)is injected in the site of exposure of exposure(intervention group) control group will receive normal pulp capping procedure by MTA follow up will be one year

Detailed description

intervention group:patient with deep caries lesion ,free from sign and symptoms of irreversible pulpitis the blood sample will be taken before the beginning of dental treatment..PRF will be obtained by blood centrifugal and injected in the site of exposure covered by glass ionomer restoration control group: patient with same condition will receive pulp capping procedure by MTA followed by glass ionomer restoration

Interventions

PROCEDUREPRF pulp capping

PRF is injected in the site of exposure

PROCEDUREMTA pulp capping

conventional pulp capping procedure

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

25 Years to 45 Years

Healthy volunteers

Yes

Inclusion criteria

* deep carious lesion- no sign of irreversible pulpitis

Exclusion criteria

* old age- periapical lesion-

Design outcomes

Primary

Measure	Time frame	Description
pulp vitality	After 1 year	no sign of irreversible pulpitis or pulpal necrosis

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026