Post-Surgery Extracorporeal Life Support

Outcomes' Predictors in Post-Surgery Extracorporeal Life Support

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04330651

Acronym

PC-ECLS

Enrollment

500

Registered

2020-04-01

Start date

2004-01-31

Completion date

2029-01-31

Last updated

2021-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiogenic Shock, Extracorporeal Life Support, Extracorporeal Membrane Oxygenation Complication, Post Cardiac Arrest Syndrome, Post-cardiac Surgery

Keywords

extracorporeal life support, ecls, ecmo, outocome, prognostic factors, extracorporeal membrane oxygenation

Brief summary

Extracorporeal Life Support (ECLS) may provide pulmonary and circulatory support for patients with acute heart failure refractory to conventional medical therapy. However, indications and effectiveness of ECLS engagement post-surgery remains a concern. The investigators sought to analyze indications, modality and outcomes of PS-ECLS, to identify predictors of early and midterm survival after PS-ECLS. The investigators have recorded prospectively, and analysed data of 209 consecutive PS-ECLS patients between January 2004 and December 2018. Demographic and clinical data before, during and after PS-ECLS were collected and their influence on hospital mortality and outcomes (early and midterm) will analyse. Multivariate analysis of pre PS-ECLS implantation factors (as age, female sex , insulin-dependent diabetes, pulmonary hypertension, STS, type of surgical procedure data, pre-ECLS blood lactate level) will be made for identify prognostic risk factors of in-hospital mortality. Overall survival will be analysed, at 6 months,1-year and 5-years, respectively and the factors influencing mild/term outcome will be investigated.

Interventions

PROCEDUREECLS

Emergency application of Extracorporeal Life Support in post-surgical patients

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Inclusion criteria

* Patients underwent cardiac surgery

Exclusion criteria

* Age \< 18 years

Design outcomes

Primary

Measure	Time frame	Description
Survival	1 month after surgery	Evaluate Early, mid and late Survival

Secondary

Measure	Time frame	Description
Prognostic factors	Early: 1 month after surgery	Identify early and late negative and positive prognostic factors
Prognostic Factors	Late: 5 years after surgery	Identify early and late negative and positive prognostic factors

Countries

Italy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026