Allergy;Food
Conditions
Keywords
food allergy, peanut, legumes, sensitization
Brief summary
The objectives of this study are to determine in children allergic to peanut (i) the prevalence of sensitization to other legumes, (ii) the prevalence of allergy to each legume in patients who are sensitized to it (iii ) the severity of the allergy to legumes other than peanut
Detailed description
Allergy to legumes is more and more frequent, especially in children allergic to peanut, with some severe reactions but little is known about cross-reactivity and clinical meanings of legumes sensitization in children allergic to peanut. All children with a confirmed peanut allergy and followed at the University Hospital of Nancy between January 1st 2017 and February 29th 2020 will be included in order to evaluate the prevalence of sensitization and allergy to other legumes in this population. In children allergic to peanut and to at least one other legume, we will evaluate the severity of the allergy and the sIgE profiles for peanut.
Interventions
None listed
Sponsors
Central Hospital, Nancy, France
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
1 Years to 18 Years
Inclusion criteria
* Confirmed allergy to peanut
Exclusion criteria
* no available information regarding sensitization and tolerance to legumes
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| sensitization to legumes | 2017 to 2020 | skin and sIgE sensitization |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| allergy to legumes | 2017 to 2020 | history of allergic reaction or oral food challenge |
| severity of allergy to legumes | 2017 to 2020 | history of allergic reaction or oral food challenge |
Outcome results
None listed