Fluid Absorption in Patients Undergoing Operative Hysteroscopy; Results From a Prospective Controlled Study

The Impact of Spinal Anesthesia and Use of Oxytocin on Fluid Absorption in Patients Undergoing Operative Hysteroscopy; Results From a Prospective Controlled Study

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04328870

Enrollment

Registered

2020-03-31

Start date

2018-05-20

Completion date

2019-09-30

Last updated

2020-03-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fluid Overload

Brief summary

To determine if combining intravenous oxytocin infusion and spinal anesthesia will reduce the amount of glycine absorption in patients undergoing operative hysteroscopy

Detailed description

Prospective controlled study in premenopausal patients who had hysteroscopic surgery including endometrial resection, endometrial polypectomy, myomectomy resection and uterine septal resection. The effect of combined spinal anesthetic with oxytocin infusion on fluid deficit was studied.

Interventions

OTHERoxytocin and spinal anesthesia

start oxytocin 10 IU/200 ml saline at the insertion of the spinal anesthesia

OTHERGeneral anesthsia

General anesthesia alone.

Study design

Allocation

NON_RANDOMIZED

Intervention model

FACTORIAL

Primary purpose

PREVENTION

Masking

NONE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 49 Years

Healthy volunteers

Inclusion criteria

* premenopausal with no cardiovascular comorbidities

Exclusion criteria

* endometrial cancer cases, patients who received pre-operative hormonal preparations, previously resected cases and cases done using bipolar diathermy.

Design outcomes

Primary

Measure	Time frame	Description
fluid overload	16 months	Fluid (glycine) excessive absorption into the patient

Countries

Jordan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026