Periodontal Diseases, Gingivitis, Hypertension
Conditions
Brief summary
Treated hypertensive patients with any form of periodontal diseases will be randomized to either supragingival dental plaque removal using electric toothbrushes at home or intensive professional oral hygiene treatment and the effects on blood pressure will be identified.
Interventions
BEHAVIORALelectric toothbrush
Participants will be instructed to use their electric toothbrushes twice a day for controlling oral plaque
PROCEDUREProfessional oral hygiene
Professional oral hygiene using ultrosound scaling and root planing
Sponsors
University of L'Aquila
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
35 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* Treated hypertension * Have at least 20 natural teeth * Presence of any form of periodontal diseases according to guidelines * Absence of other significant oral infections.
Exclusion criteria
* Secondary hypertension (known plasma renin screening, abdominal ultrasound with doppler and other investigations) * Individual is pregnant or nursing * Primary pulmonary hypertension * Professional oral hygine within past 6 months * Flu, rhinitis, sinusitis etc. within past 4 weeks * Use of antibiotics within past 4 weeks * Hospitalization for any reason within the past 3 months * Allergic disorders; History of chronic infectious disease, * Chronic hepatitis B or C infection * Chronic Obstructive Pulmonary Disease (COPD), tuberculosis * Other known chronic inflammatory or autoimmune condition such as lupus or rheumatoid arthritis, ulcerative colitis or Crohn's disease * Use of systemic or local steroids or immunosuppressive agents within 6 months of the inclusion. * History of alcohol abuse or unwillingness to limit alcohol consumption to less than 4 drinks per week
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Systolic and Diastolic Blood Pressure Change | 1 week | Ambulatory Blood Pressure Monitoring |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Systolic and Diastolic Blood Pressure Change | 1 week | Unattented Blood Pressure Measurement |
Other
| Measure | Time frame |
|---|---|
| Periodontal Health Score - Bleeding on probing (BoP) | 1 week |
| Periodontal Health Score - Periodontal Probing Depth (PPD) | 1 week |
| Periodontal Health Score - Clinical Attachment Loss (CAL) | 1 week |
Contacts
Primary ContactDavide Pietropaoli, DDS, PhD
Backup ContactRita Del Pinto, MD. PhD
Outcome results
None listed