Effect of Removal of Double Antibiotic Paste on Post Operative Pain

Influence of Different Methods of Removal of Double Antibiotic Paste as an Intracanal Medication on Post Operative Pain:a Randomized Clinical Trial

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04327453

Enrollment

Registered

2020-03-31

Start date

2020-04-30

Completion date

2020-11-30

Last updated

2020-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Effects of the Elements

Brief summary

Recruited patients with necrotic pulp after application of double antibiotic paste are assigned to group (XP Endo Finisher file) and group( Passive ultrasonic irrigation) and group (conventional syringe irrigation with side vented needle) to remove intracanal medication and record postoperative pain afterwards.

Detailed description

The investigator will recruit patients who are found eligible to the criteria, double antibiotic paste will be inserted inside the canals. After 7 days, patients will be randomly assigned to either removal of intracanal medication using, the XP-Endo Finisher file, passive ultrasonic irrigation (PUI) and conventional syringe irrigation with side vented needle. After the visit, patients will be asked to record post operative pain by Visual Analog Scale)in a given sheet

Interventions

DEVICEdouble antibiotic paste with XP-endo Finisher file

XP-endo Finisher files (FKG Dentaire, La Chaux-de-Fonds, Switzerland). file will be used with an endodontic motor X-Smart (Dentsply Sirona, Ballaigues, Switzerland) in removal of double antibiotic paste

DEVICEdouble antibiotic paste with Irrisafe Ultrasonic tip

passive ultrasonic irrigation (PUI) with an IrriSafe Ultrasonic tips (Acteon,France), which will be driven by an ultrasonic device (Newtron P5, Satelec, Acteongroup, Merignac, France) in removal of double antibiotic paste

DEVICEdouble antibiotic paste with side vented needle

conventional syringe irrigation with side vented needle (prime Dent, India) in removal of double antibiotic paste

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Outcomes Assessor)

Masking description

double

Eligibility

Sex/Gender

ALL

Age

20 Years to 50 Years

Healthy volunteers

Yes

Inclusion criteria

* Medically free patients. * Patient's age between 20-50 years. * Both sexes. * Necrotic pulp as indicated by thermal or electric pulp testing. * No history of previous endodontic treatment of the tooth. * Enough crown structure for adequate isolation.

Exclusion criteria

* Pregnancy or lactation * Medically compromised patients * Previous endodontic therapy of the affected tooth. * Teeth diagnosed with vital pulp. * Teeth with periodontal pocket more than 3mm deep. * Teeth with abnormal anatomy or calcified canals. * Teeth with caries below the bony level (non-restorable tooth). * Immature teeth with open apices.

Design outcomes

Primary

Measure	Time frame	Description
change in post operative pain (Visual Analogue Scale)	Intrappointment at 4,24,48,72 and 96 hours	Numerical (0-10)

Countries

Egypt

Contacts

Primary ContactShaimaa Nasr El-din Abd El-Ghaffar, MsC

dr_shimes@hotmail.com+0201020271788

Backup ContactReham Hassan, Ass.prof

reham-hassan@live.com+0201001542529

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026