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Radiographic and Histological Evaluation of Regenerated Bone After Grafting Using Allograft Shell and Autogenous Chips

Evaluation of Anterior Alveolar Ridge Reconstruction With Allogenic Bone Plate and Autogenous Cortical Bone Chips: A Radiographic and Histological Clinical Study

Status
Completed
Phases
Phase 4
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04324697
Acronym
Shell grafting
Enrollment
10
Registered
2020-03-27
Start date
2018-04-08
Completion date
2019-09-05
Last updated
2020-06-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alveolar Bone Resorption

Keywords

Allograft, Autogenous chips, Horizontal augmentation, Khoury shell technique

Brief summary

The clinical cases in the present study described the khoury shell technique using an allograft plate and autogenous chips, for horizontal reconstruction of the anterior alveolar ridge in the esthetic zone. Without need to use autogenous bone graft techniques that are characterized by more aggressive surgery.

Interventions

PROCEDUREHorizontal alveolar bone augmentation

Horizontal augmentation in anterior maxilla using allograft shell and autogenous chips with no need for a second surgical site

Sponsors

Ain Shams University
CollaboratorOTHER
October 6 University
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE

Intervention model description

Reconstruction of the localized deficient anterior maxilla using an allograft cortical bone plate, which was fixed at a distance from the alveolar ridge using two micro-screws, and the created gap between the allograft plate and the alveolar ridge was filled with autogenous cortical bone chips harvested intraorally using a bone scrapper.

Eligibility

Sex/Gender
ALL
Age
18 Years to 50 Years
Healthy volunteers
No

Inclusion criteria

* Patients with class IV of Cawood and Howell classification in the anterior maxilla. * Males and females 18-50 years of age. * Patients with adequate oral hygiene. * Patients with healed sites for at least 6 months after tooth extraction. * Patients with an inter-arch distance of at least 6 mm. * Compliance with all requirements in the study and signing the informed consent.

Exclusion criteria

* Patients with diseases of the immune system or systemic disease affecting bone healing * Patients who are chronic users of medications known to affect the periodontal status. * Patients with history of intravenous and/or oral bisphosphonate use. * Pathologic lesions or acute infection in the area of defect. * Patients who are pregnant or lactating mothers. * Heavy smokers who smoke more than 10 cigarettes a day. * Patients with poor oral hygiene that are not amenable to motivation and improvement. * Patients with history of irradiation of the head and neck region. * Vulnerable patients.

Design outcomes

Primary

MeasureTime frameDescription
Alveolar Bone quantity6 monthsAlveolar bone width by millimeters using Cone Beam Computed Tomography

Secondary

MeasureTime frameDescription
Alveolar Bone quality7 monthsHistological evaluation of status of regenerated bone vitality and remodeling

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026