Brain Aging in Mexican Americans
Conditions
Brief summary
By doing this study we are trying to learn more about brain aging in Mexican Americans. Participants will be asked to complete a screening visit to determine if it is safe to undergo a PET scan. If eligible, participants will undergo a medical procedure that takes a picture of their brain. This procedure is called a PET scan of the brain.
Interventions
DIAGNOSTIC_TESTPET scan of the brain with Flortaucipir
PET scan of the brain with non FDA approved Radio tracer.
Sponsors
Sid E. O'Bryant
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
50 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Participation in the Health & Aging Brain Study: Health Disparities Amyloid Project
Exclusion criteria
* Not a participant in the Health & Aging Brain Study: Health Disparites Amyloid Project * Medical condition that precludes safe use of PET tracer
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Tau Accumulation Measured by PET Imaging | 4 weeks | Tau PET scan completed and radiologist reviewed imaging and provided a report on whether or not Tau protein was present in the brain. |
Countries
United States
Participant flow
Participants by arm
| Arm | Count |
|---|---|
| Tau Scan Completed Participants completed screening and Tau PET scan | 12 |
| Total | 12 |
Baseline characteristics
| Characteristic | Tau Scan Completed |
|---|---|
| Age, Categorical <=18 years | 0 Participants |
| Age, Categorical >=65 years | 5 Participants |
| Age, Categorical Between 18 and 65 years | 7 Participants |
| Ethnicity (NIH/OMB) Hispanic or Latino | 12 Participants |
| Ethnicity (NIH/OMB) Not Hispanic or Latino | 0 Participants |
| Ethnicity (NIH/OMB) Unknown or Not Reported | 0 Participants |
| Region of Enrollment United States | 12 participants |
| Sex: Female, Male Female | 10 Participants |
| Sex: Female, Male Male | 2 Participants |
Adverse events
| Event type | EG000 affected / at risk |
|---|---|
| deaths Total, all-cause mortality | 0 / 16 |
| other Total, other adverse events | 0 / 16 |
| serious Total, serious adverse events | 0 / 16 |
Outcome results
Primary
Tau Accumulation Measured by PET Imaging
Tau PET scan completed and radiologist reviewed imaging and provided a report on whether or not Tau protein was present in the brain.
Time frame: 4 weeks
Population: No analysis completed. Only aim was to complete Tau PET scans
| Arm | Measure | Value (COUNT_OF_PARTICIPANTS) |
|---|---|---|
| Tau PET Scan Completed | Tau Accumulation Measured by PET Imaging | 12 Participants |