Arthroscopic Knee Surgery, Dexmedetomidine, Intra-articular, Lidocaine 5% Patch
Conditions
Brief summary
Surgery of the knee is a very common procedure which can be very painful and sufficient postoperative pain treatment is often problematic. The aim of this work was to study the effects of supplementation of intra-articular bupivacaine dexmedetomidine with lidocaine 5% patch after arthroscopic knee surgery under general anesthesia and its role in improving quality of anesthesia.
Interventions
DRUGLidocaine 5% patch with Dexmedetomidine Bupivacaine
10 ml 0.5 % Bupivacaine and 1µg/kg Dexmedetomidine diluted in 10 ml saline was injected intra-articularly through one of the arthroscopic ports after the end of the surgery under complete aseptic technique and a patch of lidocaine 5% was applied to the skin between the arthroscopic ports
10 ml 0.5 % Bupivacaine and 1µg/kg Dexmedetomidine diluted in 10 ml saline was injected intra-articularly through one of the arthroscopic ports after the end of the surgery under complete aseptic technique without a patch of lidocaine 5%
Sponsors
Tanta University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Intervention model description
Patients were allocated into 2 groups, 20 patients in each received 10 ml 0.5 % bupivacaine and 1µg/kg dexmedetomidine diluted in 10 ml saline injected intra-articularly; group A: no patch, group B: a patch of lidocaine 5% was applied to the skin.
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
* Adult patients * ASA I & II * Aged between 18 to 60 years * Weight between 60 to 100 kg * Scheduled for elective arthroscopic knee surgery
Exclusion criteria
* patient refusal. * history of cardiac disease. * impaired renal or hepatic function. * hypertension treated with α methyldopa, clonidine, or beta-adrenergic blockers. * if they have used opioid analgesics within the previous 24 hr. * previous sensitivity to local anesthetics.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The total dose of postoperative pethidine consumption | 24 hours | The total dose of postoperative pethidine consumption; Pethidine 20 mg was given as rescue analgesia if pain visual analogue visual analogue scale (VAS) ≥4. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| First postoperative analgesia request time | 24 hours | First postoperative analgesia (Pethidine 20 mg) request time |
| Pain intensity | 24 hours | Visual analogue scale (VAS) was recorded immediately postoperative and at 30 min, 1, 2, 4, 6, 12 and 24 hours postoperatively. The score ranges from 0 to 10; higher means worse pain |
Outcome results
None listed