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Clinical Practice Guideline for Neonatal Extravasation Injury

Clinical Practice Guideline on the Prevention and Management of Neonatal Extravasation Injury

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04321447
Enrollment
213
Registered
2020-03-25
Start date
2015-11-14
Completion date
2017-08-29
Last updated
2020-03-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Extravasation Injury

Keywords

Intravenous nursing, Newborn infant, Neonatal intensive care units, Evidence-based professional practice

Brief summary

This study is aimed to evaluate the effectiveness of an evidence-based clinical practice guideline in the prevention and management of neonatal extravasation injury, and to examine the change in nurses' knowledge of and adherence to the guideline.

Detailed description

A study with controlled before-and-after design was conducted. The clinical practice guideline was developed and a multifaceted educational program was delivered for nurses. Neonatal outcomes were collected at baseline and after completion of the intervention. The changes in nurses' level of knowledge and adherence to the guideline were also measured.

Interventions

OTHERClinical practice guideline for prevention and management of extravasation injury

Implementation of an evidence-based clinical practice guideline and delivery of an educational programme for nurses

Sponsors

United Christian Hospital
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
SEQUENTIAL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
No minimum to 1 Years
Healthy volunteers
No

Inclusion criteria

* Neonates who were admitted for intravenous medication or infusion therapy, and * Neonates whose parents were equal to or over 18 years old and able to communicate in Chinese or English.

Exclusion criteria

* Neonates who were born with congenital dermatological problems such as ichthyosis and epidermolysis bullosa.

Design outcomes

Primary

MeasureTime frameDescription
Change in rate of peripheral intravenous extravasationChange from Baseline rate at one monthThe number of the incidents divided by the total number of catheter days and multiplied by 1,000
Change in rate of extravasation from a central lineChange from Baseline rate at one monthThe number of the incidents divided by the total number of catheter days and multiplied by 1,000

Secondary

MeasureTime frameDescription
Change in nurses' level of knowledgeChange from Baseline Knowledge level at six monthsThe Neonatal Extravasation Knowledge Test
Change in nurses' adherence to clinical practice guidelinesChange from Baseline Adherence level at six monthsA 27-item audit tool

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 25, 2026