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COVID-19 Pandemic Response Network

Pandemic Response Network: Duke Community Health Watch

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04320862
Enrollment
9207
Registered
2020-03-25
Start date
2020-04-03
Completion date
2021-04-30
Last updated
2021-09-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronavirus, COVID-19, Influenza -Like Illness, Lower Resp Tract Infection, SARS-CoV-2, Upper Resp Tract Infection

Brief summary

Coronavirus Disease 19 (COVID-19) represents an unprecedented challenge to the operations and population health management efforts of health care systems around the world. The Pandemic Research Network (PRN): Duke Community Health Watch study leverages technology, clinical research, epidemiology, telemedicine, and population health management capabilities to understand how to safely COVID-19. The target population is individuals in the Duke Health region as well as individuals beyond the Duke Health region who have flu-like symptoms, a viral test order for COVID-19, confirmed COVID-19, or concern for exposure to COVID-19. A subgroup of particular interest within the target population is health care workers (HCW) and families of HCW. Community members will enroll in the study electronically and for 28 days will be reminded via email or SMS to submit signs and symptoms related to COVID-19. Participants who report symptoms will be provided information about COVID-19 testing (if needed) and established mechanisms to seek care within Duke Health. Instructions for telemedicine and in-person visits, which is available publicly at https://www.dukehealth.org/covid-19-update, will be presented to participants. Participants who are unable to report symptoms independently may be contacted via telephone by Population Health Management Office (PHMO) or Clinical Events Classification (CEC) team members. Data collected through the Pandemic Response Network (PRN): Duke Community Health Watch study will be used for three objectives. * First, to characterize the epidemiological features of COVID-19. Specifically, we will have a high-risk subgroup of HCW and families of HCW that we enroll. * Second, to develop models that predict deterioration and the need for inpatient care, intensive care, and mechanical ventilation. * Third, to develop forecast models to estimate the volume of inpatient and outpatient resources needed to manage a COVID-19 population. The primary risk to study participants is loss of protected health information. To address this concern, all data will be stored in Duke's REDCap instance and the Duke Protected Analytics Compute Environment (PACE).

Interventions

None listed

Sponsors

Duke University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
Yes

Inclusion criteria

* flu-like symptoms * a viral test order for COVID-19 * confirmed COVID-19 * concern for exposure to COVID-19

Exclusion criteria

\- None

Design outcomes

Primary

MeasureTime frame
Number of participants who experience inpatient admission2 months

Secondary

MeasureTime frame
Number of participants admitted to the intensive care unit2 months
Number of participants requiring mechanical ventilation2 months
Number of deceased participants2 months

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026