Adhesive Small Bowel Obstruction
Conditions
Keywords
Adhesive small bowel obstruction, Laser acupuncture, Acupuncture
Brief summary
Adhesive small bowel obstruction (ASBO) is one of the most common complications and is a major cause of admission after intra-abdominal surgery. To date, the ideal management of ASBO remains controversial. The aim of this protocol designed as a double-blind randomized controlled trial is to investigate the efficacy of laser acupuncture (LA) therapy in patients with ASBO.
Interventions
PROCEDURELaser acupuncture
Laser acupuncture is a non-invasive therapy that involves stimulation of traditional acupoints with low-intensity, non-thermal laser irradiation.
Sponsors
Chang Gung Memorial Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Caregiver, Outcomes Assessor)
Masking description
The participants in each group will receive real (with energy output) or sham (without energy output) laser acupuncture. The feelings of participants in each group are not different. The care provider and outcomes assessor don't involve the random allocation and don't know if participants receive real laser acupuncture.
Eligibility
Sex/Gender
ALL
Age
20 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* Aged 20 to 80 years * Clinical symptoms and signs of mechanical obstruction
Exclusion criteria
* Clear non-adhesive etiology of small bowel obstruction (e.g. tumor, hernia) * Emergency surgical intervention before being admitted to the hospital * Pregnancy * Local skin infection on the acupoints, and limb amputees.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Success rate of conservative treatment | 2 week | Defined as no need for long term nasogastric tube decompression and operative intervention. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Time to oral intake | 2 weeks | Defined as participants can try intake due to symptoms improved including nausea, vomiting, distension and pain. |
| Length of hospital stay | Through study completion, an average of 1 year | Date from admission to discharge |
| Serum lipase | Up to 2 weeks | Serum lipase |
| Serum amylase | Up to 2 weeks | Serum amylase |
| Serum cortisol | Up to 2 weeks | Serum cortisol |
| Serum motilin | Up to 2 weeks | Serum motilin |
| Serum ghrelin | Up to 2 weeks | Serum ghrelin |
| Serum intestinal fatty acid binding protein (I-FABP) | Up to 2 weeks | Serum intestinal fatty acid binding protein (I-FABP) |
Countries
Taiwan
Contacts
PRINCIPAL_INVESTIGATORChun-Ting Liu, MD
Department of Chinese Medicine, Kaohsiung Chang Gung Memorial Hospital
Outcome results
None listed