Obesity
Conditions
Brief summary
The study was aimed at comparing four different anthropometric parameters to cardiometabolic risk factors in overweight and obese subjects (Body Mass Index (BMI)≥25)
Detailed description
the present study was focused to compare the level of statistical association among four different anthropometric parameters, body mass index (BMI), waist circumference (WC), waist to height ratio (WHtR) and neck circumference (NC) and the cardiovascular (CV) risk factors most commonly evaluated in the clinical practice such as systolic and diastolic blood pressure, and fasting glucose, lipid (triglycerides, total, High-density lipoprotein (HDL) and Low-density lipoprotein (LDL) cholesterol), insulin, Homeostatic Model Assessment for Insulin Resistance (HOMA-IR), uric acid, 25-hydroxyvitamin D (25(OH)D), c-reactive protein (CRP), white blood cells and platelet number in a population of 1214 apparently healthy subjects with overweight and obesity subjects
Interventions
OTHERObservational
Observational
Sponsors
Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Inclusion criteria
* Overweight or obesity (BMI\> 25 Kg/m2)
Exclusion criteria
* Any kind of drug * Hypertension * Endocrine diseases (diabetes mellitus, hypo or hyperthyroidism, hypopituitarism, etc.), * Chronic inflammatory diseases * Renal failure * Liver failure * Angina pectoris * Myocardial infarction and heart failure * Genetic heart diseases * Thrombocytopenias
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Body mass index | baseline | Body mass index (BMI) (expressed in kg/m\^2) |
| waist circumference | baseline | waist circumference (WC) (expressed in cm) |
| neck circumference | baseline | neck circumference (NC) (expressed in cm) |
| waist to height ratio | baseline | waist to height ratio (WHtR) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| fasting blood glucose | baseline | fasting blood glucose (FBG) (expressed in mg/dL) concentration in serum |
| HDL Cholesterol | baseline | HDL Cholesterol (expressed in mg/dL) concentration in serum |
| Insulin | baseline | Insulin (expressed in mg/dL) concentration in serum |
| Homeostasis model assessment: insulin resistance | baseline | Homeostasis model assessment: insulin resistance index (HOMA-IR) |
| Intima-media thickness | baseline | Intima-media thickness (IMT) (expressed in mm) |
| Platelets | baseline | Platelets (expressed in 10\^3/µL) concentration in serum |
| white blood cells | baseline | white blood cells (WBC) (expressed in 10\^3/µL) concentration in serum |
| Vitamin D | baseline | Vitamin D (expressed in ng/dL) concentration in serum |
| C-reactive Protein | baseline | C-reactive Protein (CRP) (expressed in mg/dL) |
| LDL Cholesterol | baseline | LDL Cholesterol (expressed in mg/dL) concentration in serum |
| Blood pressure | baseline | blood pressure (BP) expressed in mmHg |
| Total Cholesterol | baseline | Total Cholesterol (expressed in mg/dL) concentration in serum |
| Triglyceride | baseline | Triglyceride (expressed in mg/dL) concentration in serum |
Countries
Italy
Outcome results
None listed