Skip to content

Evaluation of OCT and Visual Field Changes After Vitrectomy and ILM Peeling

Evaluation of OCT and Visual Field Changes After Vitrectomy and ILM Peeling

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04312620
Enrollment
10
Registered
2020-03-18
Start date
2020-04-30
Completion date
2021-04-08
Last updated
2020-03-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ILM Peeling

Brief summary

To evulate changes in VF and OCT after viterctomy associated with ILM peeling.

Detailed description

Macular epiretinal membrane (ERM) is a disorder of the vitreomacular interface characterized by fibrocellular proliferation on the anterior surface of the internal limiting membrane (ILM) of the macula. Pars plana vitrectomy with ERM removal and inner limiting membrane peeling is the standard surgical treatment for an ERM. ILM peeling is performed to eliminate the scaffold for myofibroblast proliferation and any microscopic ERM in order to prevent ERM recurrence. ILM peeling is indicated for other pathologies other than ERM such as, diabetic macular edema, and macular hole. ILM peeling is a traumatic procedure that may have many effects on the underlying inner retinal layers that may lead to changes in retinal function. Retinal edema, eccentric scotoma, dissociation of the nerve fiber layer, iatrogenic punctuate chorioretinopathy, and subretinal, retinal, and vitreous hemorrhage are well described secondary to the surgical trauma of peeling in addition to stain toxicity. Investigation of these changes may assist in aiding the development of minimally traumatic techniques for ILM removal . Evaluation of functional changes may include visual field and Multifocal electroretinography assessment. Visual field defect after vitrectomy a well known post operative complication usually in eyes that underwent fluid air exchange, the cause of visual field defect remain unclear. Optical Coherence Tomography (OCT), imaging is done to evaluate inner retinal layers after ILM peeling,High myopic eyes might develop more severe, scattered inner retinal defects after ILM peeling.

Interventions

None listed

Sponsors

Assiut University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
No minimum to 80 Years
Healthy volunteers
No

Inclusion criteria

1. 1-Idiopathic ERM, 2. Primary full thickness macular hole, 3. Lamellar macular hole, and 4. Vitromacular traction.

Exclusion criteria

* 1-Patients with a secondary ERM, 1. diabetic retinopathy, 2. venous occlusion, 3. retinal detachment, 4. uveitis, and 5. trauma. 2-Other ocular pathologies that could interfere with the functional results <!-- --> 1. dense cataract , 2. glaucoma, and 3. previous retinal surgery.

Design outcomes

Primary

MeasureTime frameDescription
BCVA6 monthsILM peeling

Contacts

Primary Contactalmoatz bellah zohier mohamm,ed, master
moatazmoh58@gmail.com01099490013
Backup Contactmagady mostafa, professor

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026