Anterior Approach, Hip Arthropathy, Hip Osteoarthritis, Minimal Invasive, Tissue Injury
Conditions
Brief summary
Total hip arthroplasty is a method of choice for treating advanced osteoarthritis of the hip and one of the most frequent orthopedic procedures. Of all hip surgical approaches described, the tendency for minimally invasive techniques has been dominated over the last few years due to faster patient mobilization, reduced postoperative pain and need for blood transfusion. Two of the most common approaches used for minimally invasive total hip arthroplasty are: AMIS anterior approach and mini-posterior approach, which is a modification of the standard posterior approach. The purpose of this study is the biochemical, imaging and clinical evaluation of the tissue damage caused by the above-mentioned techniques of minimally invasive total hip arthroplasty.
Interventions
PROCEDUREMini posterior approach Total Hip Replacement
Total hip replacement in patients suffering from hip osteoarthritis using the mini posterior approach
PROCEDUREAnterior approach total hip replacement without a traction table
Mini Anterior approach total hip replacement in patients suffering from hip osteoarthritis without the aid of a traction table
PROCEDUREAnterior approach total hip replacement with a traction table
Mini Anterior approach total hip replacement in patients suffering from hip osteoarthritis with the aid of a traction table
Sponsors
National and Kapodistrian University of Athens
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients that sign the Informed consent * Patients aged 18 years and over who are going to undergo primary total hip arthroplasty
Exclusion criteria
I. Active infection II. Previous hip operation in any leg III. Any kind of operation the past 3 months IV. Obesity (BMI, Body Mass Index \>30) V. Autoimmune diseases or myositis of any etiology VI. Active cancer
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Tissue damage change | Change from 6 to 24 and then 48 hours post-surgery | Investigate and quantify at the biochemical level with all available biomarkers the extent of tissue damage caused during a hip arthroplasty between different hip surgical approaches. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Imaging | Day 30 after surgery | All patients will be subjected to imaging with a hip MRI |
| Clinical Tests change | Change to clinical test from Day 2 to day 15 and then day 30 post-surgery | All patients will be monitored postoperatively for the prescribed period and data will be recorded. |
Countries
Greece
Contacts
Primary ContactVasileios Nikolaou
Outcome results
None listed