Interactive E-health Database for the Identification of Potential Interactions Among Drugs Prescribed to CKD Patient

Development of an Interactive E-health Database Aimed to Identify Potential Interactions Among Drugs Prescribed to Chronic Kidney Disease (CKD) Patient

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04310501

Enrollment

150

Registered

2020-03-17

Start date

2020-04-23

Completion date

2022-03-31

Last updated

2021-05-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Renal Insufficiency, Chronic

Keywords

Drug Interactions, Polymorphism, Genetic, Pharmacogenetics, Databases, Pharmaceutical

Brief summary

The aim of the current project is the development and implementation of an e-health database of drug interactions (drug-drug, drug-food, drug-alcohol and drug-herbal products interaction) to CKD patients in order to achieve a holistic approach to patient care and personalized medicine. The study will be conducted in the University of Ioannina (cooperation between the Department of Nephrology and the Laboratory of Physiology). Data will be collected form 150 CKD patients (Stages 1-5 pre-dialysis, undergoing dialysis, kidney transplantation). Sixty patients will be selected for the pilot study which will include blood and urine tests and specific polymorphism analysis (pharmacogenetic tests). Pilot implementation of the e-health database will be undertaken by health professionals of the Department of Nephrology (University Hospital of Ioannina) to test the system in realistic setting (usability, efficiency and efficacy) in order to make the necessary changes prior to full scale deployment.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Age\>18 years * CKD diagnosis according to KDOQI Guidelines * absence of active malignancy * absence of decompensated heart failure New York Heart Association (NYHA) IV * absence of liver cirrhosis * patient's consent

Exclusion criteria

* Age\<18 years * active malignancy * decompensated heart failure NYHA IV * liver cirrhosis * patient's refusal to participate in the study

Design outcomes

Primary

Measure	Time frame	Description
E-health database	1-12 months until completion of patients recruitment	E-health database of drug interactions (drug-drug, drug-food, drug-alcohol and drug-herbal products interaction) to CKD patients in order to achieve a holistic approach to patient care and personalized medicine.

Countries

Greece

Contacts

Primary ContactEvangelia Ntounousi, PHD

evangeldou@gmail.com+302651099653

Outcome results