Cardioplegia Solution Adverse Reaction, Coronary Artery Bypass Grafting (CABG), Heart Attack
Conditions
Keywords
heart attack, cardioplegia solution, Minimal extracorporeal circulation system (MiECC), Myocardial protection system (MPS), Coronary artery bypass grafting (CABG)
Brief summary
The goal of this study is to compare the two cardioplegia solutions (blood cardioplegia by means of MPS ® vs. Cardioplexol ®) regarding perioperative outcome and with special attention to cardiac markers in patients with a recent heart attack.
Interventions
OTHERMyocardial protection system (MPS)
cardioplegia solution, A separate pumpsystem by which Blood cardioplegia with individually composable additives as cardioplegia solution can be used
OTHERCardioplexol
cardioplegia solution
Sponsors
University Hospital, Basel, Switzerland
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Inclusion criteria
* Patients who underwent a CABG using MPS® or Cardioplexol ® * Heart attack less than 7 days before surgery
Exclusion criteria
* use of other cardioplegia solution than Cardioplexol ® or MPS® * other inventions than CABG * explicit will of the patient that his data may not be used * denied general consent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| myocardial damage | patients with that received a coronary artery bypass grafting and that were treated (for approximately 15 days) at the University Hospital between February 2010 and January 2020 (data taken perioperative during hospital stay for CABG) | Analyse cardiac biomarkers as indicators for myocardial damage: high sensitive troponin (Ths-TrT, ng/mL), creatine kinase (CK, in ng/mL) and creatine kinase-MB isoenzyme (CK-MB, in ng/mL) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| 30 days Mortality | 30 days after CABG | death after coronary artery bypass grafting |
| length of stay in the intensive care unit | perioperative during hospital stay for CABG (for approximately 15 days) | duration of stay at intensive care unit |
| Number of participants with bleedings | perioperative during hospital stay for CABG (for approximately 15 days) | bleeding complication after coronary artery bypass grafting |
| Number of participants with postoperative arrhythmia | perioperative during hospital stay for CABG (for approximately 15 days) | rhythm disturbance after coronary artery bypass grafting |
Countries
Switzerland
Outcome results
None listed