Arthropathy Hemophilic, Hemophilia
Conditions
Keywords
Hemophilia, Arthropathy, Physiotherapy, Manual therapy, Joint health
Brief summary
Uncertainty about how to treat existing hemophilic arthropathy (HA) is the most important issue that will increase functionality and joint health. Recent studies have shown that MT can be used safely for improving joint health, pain and ROM with no bleedings in PwH with elbow and ankle HA. Unlike MT studies in hemophilia, we investigated the effects of MT on important parameters such as muscle strength (MS), functional level, joint health, functional independence score in hemophilia (FISH) and kinesiophobia. These parameters are closely related to functional level and quality of life of PwH. Therefore, evaluation of these parameters and determining the effects of the MT on these parameters are very important for both PwH and also clinicians.
Detailed description
The aim of this study was to investigate the effects of manual therapy in addition to home exercise program on hemophilia functional independence level, joint health, kinesiophobia, functional level, range of motion, muscle strength and pain level in hemophilic individuals with lower extremity joint arthropathy. Hemophilic arthropathy was developed in at least one of the lower extremity joints and aged between 18-30 years 17 severe type hemophilic men were participated in the study. The participants were divided into two groups as Home Exercise Group (HEG) and Manual Therapy Group (MTG) by randomization method. While the HEG was performed the exercise program at home, in addition to the same HEG manual therapy were applied to the MTG by the same physiotherapist 3 days a week for 1 hour. Both groups were followed for a total of 5 weeks and pre-treatment evaluations were repeated post-treatment. The joint health of the hemophilics in both groups were evaluated with Hemophilia Joint Health Score (HJHS), their kinesiophobia level were evaluated with Tampa Kinesophobia Scale, their functionality with the Functional Independence Score in Hemophilia (FISH). In addition, Functional Reach, Timed Up and Go and 5 Times Sit-to- Stand tests were used for functional level. The range of motion was evaluated with a goniometer, muscle strength was measured with a digital dynamometer and pain level was assessed with a Visual Analogue Scale (VAS). Number of hemarthrosis decreased in both groups.
Interventions
OTHERManual therapy
Both groups received for 3 sessions per week, a total of 5 weeks. Home exercises were performed by the patient for 30 minutes at home.In home exercises active ROM for warm-up (5 min), passive stretchening (5 min), strengthening exercises (10 min), proprioceptive and balance exercises (10 min). In manual therapy group, myofascial release techniques (MRT) and Kalternborn mobilization techniques lasted about one hour. In MRT, each manuever was applied for 2 mins and 3 times. The superficial strokes were performed, assisted by slight movements of joints. MRT to posterior capsule of the knee, ligaments, iliotibial tractus, plantar fascia, metatarsal, tarsals, and toes. Kalterborb mobilization tecnqiues; posterior gliding for restricted knee flexion, anterior gliding for restricted knee extension,talocrural posteior gliding for dorsal flexion, talocrural anterior gliding for plantar flexion.3 \* 10 repetitions, 20 sec of per reps and 10 sec of interval.
Sponsors
Necmettin Erbakan University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
MALE
Age
18 Years to 30 Years
Healthy volunteers
No
Inclusion criteria
* Patients with hemophilia who have arthropathy developed in any of the lower extremity joints due to severe hemophilia and to be receiving regular prophylaxis (3\*1500 IU/ per week), but not having regular physical activity and sports.
Exclusion criteria
* Patients with hemophilia who had any disease related to connective tissue, any surgery that affects lower limb function (joint debridement, fracture, prosthesis), any neurological disease or cognitive impairment that may affect functional level, any sensorial loss of peripheral nerve injury and did not attend their sessions and evaluations regularly.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Hemophilia Joint Health Score | 5 week | We used the index point of joints. Score ranged from 0 to 20. Low score indicates the good joint health |
| Functional Independence Score in Hemophilia | 5 week | We used the functional independence of patients. Score ranged from 0 to 32. High score indicates the functional independence. |
| Tampa Kinesiophobia Scale | 5 week | Score higher than 37 were associated with a high degree of kinesiophobia. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Frequency bleeding | 5 week | It was evaluated from the diaries kept by the patients |
| Functional Reach | 5 week | It was used to assess dynamic balance. |
| Range of motion | 5 week | Joint range was measured with a universal goniometer. |
| 5 Times Sit to Stand | 5 week | It was evaluated the functional strength of lower extremity, transitive movements, balance and fall risk. |
| Timed Up and Go | 5 week | It was used to evaluate functional mobility, dynamic balance, fall risk and postural stability. |
| Muscle Strength | 5 week | It was measured with hand-held dynamometer. |
| Numerical Pain Scale | 5 week | It was used for assessment of activity and resting pain. |
Countries
Turkey (Türkiye)
Outcome results
None listed