Texture Features and PDL1 in CT-PET 18 FDG

Correlation Between Texture Features With CT-PET 18 FDG and Overexpression of PDL1 in Non-small-cell Lung Carcinomas During the Initial Staging.

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04309422

Enrollment

Registered

2020-03-16

Start date

2018-04-01

Completion date

2020-01-31

Last updated

2020-03-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non Small Cell Lung Cancer

Keywords

Correlation between overexpression of PDL1, texture features, CT-PET 18 FDG, Non Small Cell Lung Carcinoma

Brief summary

Search correlation between texture features in CT-PET 18 FDG and overexpression of PDL1 in non-small cell lung carcinomas during the inital staging. The hypothesis is that overexpression of PDL1is correlated with at least one texture feature among those selected. 84 CT-PET 18 FDG at the initial staging of a non small cell lung carcinoma (adenocarcinoma or squamous cell carcinoma), whose the biopsed site was the primitive site or the drainage lymphadenopathy, without previous treatment, were recruited and analyzed by a software allowing to estimate texture features.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* adult patient ; * first CT-PET 18 FDG realized for the inital staging ; * absence of previous treatment for a thoracic neoplasm ; * biopsy realized on the primitive site or local drainage lymphadenopathy ; * primitive site viewable with morphological imagery ; * availability of evaluation of PDL1's overexpression ;

Exclusion criteria

\- Refusal to participate in this research

Design outcomes

Primary

Measure	Time frame	Description
Correlation between at least one texture feature and overexpression of PDL1	1 day	Correlation between at least one texture feature and overexpression of PDL1

Countries

France

Outcome results