Acute Pain, Analgesia, Hip Arthropathy, Pain, Postoperative Complications, Postoperative Pain
Conditions
Keywords
regional anesthesia, hip surgery, PENG
Brief summary
This study analyze the effect of Pericapsular Nerve Group (PENG) Block combined to wound infiltration for analgesia after elective hip replacement. Half of participants will receive a PENG Block combined with wound infiltration, while the other half will receive wound infiltration alone.
Interventions
PROCEDUREPENG block
After performing spinal anesthesia, PENG block with 20 mL of 0.375 % Ropivacaine will be executed as described by Giron-Arongo et al with a low frequency curvilinear probe. A 22G 80 mm needle (Stimuplex Ultra 360, Braun ) will be used.
PROCEDUREWound Infiltration
At the end of operation, the surgeon will perform wound infiltration with 20 mL of 0.375 % Ropivacaine.
Sponsors
Campus Bio-Medico University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Elective hip replacement surgery * ASA physical status score \< 4
Exclusion criteria
* Contraindications to regional anesthesia * ASA physical status score ≥ 4 * Patient's refusal or inability to sing the informed consent * Pre-operatively therapy with opioids * Allergies to any drug provided by the study protocol
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Maximum Pain Score | 24 hours | A visual analog pain scale anchored by no pain (score of 0) and pain as bad as it could be or worst imaginable pain (score of 100 \[100-mm scale\]) will be used to evaluate pain during 48 h after surgery |
| Total opioids consumption | 48 hours | Total of Sublingual Sufentanil tablets released |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Time to ambulation | 48 hours | Time until the patient is able to stand up and walk with or without assistive devices |
| Quadriceps weakness | 48 hours | Presence of weakness of the quadriceps using a scale where 0= no effect; 1 = knee flexion possible but not hip flexion; 2 = absence of knee and hip flexion |
| Time to first opioid | 48 hours | Time (hours) from the end of surgery to the first opioid administration |
| Opioids side effects | 48 hours | The presence or absence of opioids side effects such as drowsiness, desaturation, nausea and vomiting |
| Incidence of block complications | 48 hours | Any complications or side effects of the blocks, such as local infection, intravascular injection of local anesthetics and immediate systemic toxicity. |
| Range of hip motion | 24 hours | Degrees of hip flexion |
Countries
Italy
Outcome results
None listed