Evaluation of Prone Position Effect During NIV and HFNC on Acute Hypoxemic Respiratory Failure
Conditions
Keywords
Noninvasive ventilation, High-flow nasal oxygen therapy, Prone position
Brief summary
The aim of this trial is to study the effect of prone position during NIV and HFNC on acute hypoxemic respiratory patients.
Detailed description
Inclusion Criteria: Adult patients with: • ARDS/pneumonia/acute hypoxemic respiratory failure with PaO2/FiO2 between 150 and 300 (on 5 cmH2O PEEP level) Exclusion Criteria * General NIV or HFNC contraindications * Immediate need for IOT * Prone position intolerance * Patients refusal to participate Interventions: * Prone position for 2-4 hours twice a day, for 3 days (first 3 days since admission to ICU) * Nurse surveilance: at least every 15 minutes Outcomes: * Need for IOT * Effects on the measurements specified above (particularly PaO2/FiO2)
Interventions
DEVICEProne position during non-invasive respiratory support
HFNC and NIV application with patient on prone position
Sponsors
Hospital General Universitario Morales Meseguer
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Adult patients with: * ARDS/pneumonia/acute hypoxemic respiratory failure with PaO2/FiO2 between 150 and 300 (on 5 cmH2O PEEP level)
Exclusion criteria
* General NIV or HFNC contraindications * Immediate need for IOT * Prone position intolerance * Patients refusal to participate
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Oro-tracheal entubation | 1 month | Oro-tracheal entubation avoidance |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| PaO2/FiO2 | 1 month | Effect of prone position on PaO2/FiO2 |
Contacts
Primary ContactMiguel Guia, MD
Outcome results
None listed