Ultrasound Guided Erector Spinae Plane Block Combined With General Anaesthesia Versus Conventional General Anaesthesia in Lumbar Spine Surgery

ERECTOR SPINAE PLANE BLOCK COMBINED WITH GENERAL ANAESTHESIA VERSUS CONVENTIONAL GENERAL ANAESTHESIA IN LUMBAR SPINE SURGERY

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04302129

Acronym

US ESP block

Enrollment

Registered

2020-03-10

Start date

2020-01-04

Completion date

2020-04-30

Last updated

2020-03-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anaesthetic Drugs, Hypotensive Drugs, Perioperative Analgesia

Brief summary

Ultrasound guided erector spinae plain block combined with general anaesthesia versus conventional general anaesthesia in lumbar spine surgery, it's hypothesized that combined regional anaesthesia with general anaesthesia in lumbar spine surgery may reduce the anaesthetic requirements, aid in controlled hypotension and improve the perioperative pain management.

Detailed description

Primary outcomes: • Anaesthetic requirements: based on entropy monitoring(state and response entropy monitoring and the difference as a measure for adequacy of analgesia) and haemodynamic parameters ( heart rate and mean arterial blood pressure) at the following time intervals: before induction, after induction, after giving either ESP block or multimodal analgesia and starting surgical stimulus, at 30 min intervals, at end of anaesthesia, at eye opening. Secondary outcomes: * Stress response measurement based on serum cortisol and blood glucose levels * Controlled hypotensive anaesthesia: various drugs required and doses given * Intraoperative and postoperative analgesia. * Postanaesthesia care unit data concerning recovery.

Interventions

PROCEDUREErector spinae plane block

20 ml local anaesthetic are injected bilaterally on each side of the surgical incision underneath the erector spinae muscle where the dorsal rami pass around the bases of the transverse processes.

DRUGMultimodal analgesia

Ketorolac 0.75 mg/ Kg and paracetamol 10 mg/ Kg intravenously

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Investigator)

Masking description

closed envelope method

Eligibility

Sex/Gender

ALL

Age

18 Years to 70 Years

Healthy volunteers

Inclusion criteria

patients undergoing lumbar spine surgery

Exclusion criteria

* Coagulation disorders. * BMI \> 30 or \< 18.5. * Patients with surgical site infection. * Patients with unstable spine integrity like fractures or scoliosis. * Hypertensive ,cardiac and diabetic patients.

Design outcomes

Primary

Measure	Time frame	Description
Anaesthetic requirements:	the surgery period	based on entropy monitoring and haemodynamic parameters.

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026