Patients Undergoing Diagnostic Coronary Angiography
Conditions
Brief summary
To investigate whether omitting systemic anticoagulation during transradial coronary angiography and/or a distal radial access reduce the risk of postprocedural radial artery occlusion
Interventions
OTHERTraditional punkcture site and No anticoagulation
Traditional punkcture site and No anticoagulation
OTHERTraditional punkcture site and ACT-guided anticoagulation
Traditional punkcture site and ACT-guided anticoagulation
Sponsors
Prof. Dr. med. Ingo Eitel
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Clinical indication to perform diagnostic coronary angiography * Age \> 18 years * Written informed consent
Exclusion criteria
* Preexisting or already administered anticoagulation prior to coronary angiography * Planned coronary intervention * Preexisting radial artery occlusion or missing pulse at the potential puncture sites * Allergy / intolerance to anticoagulants * Active bleeding or comorbidity with elevated bleeding risk * Pregnancy * Inability to sign informed consent * Participation in another trial
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Occurrence of postprocedural RAO | Day 1 | Will be the occurrence of postprocedural RAO assessed with high-resolution vascular ultrasound. Experienced sonographers will perform color Doppler ultrasound in all study patients after removal of the compression device to examine the radial, ulnar, and brachial arteries of the access forearm. |
| Bleeding events | Day 1 | Will be bleeding events according to Bleeding Academic Research Consortium (BARC) criteria. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Sonographic characteristics of radial artery occlusion | 3 Month | Occlusion lengths or minimal residual perfusion |
Outcome results
None listed