Management of Threatened Preterm Labor by Cervical Length-based Approach or Conventional Approach

A Comparison of the Effectiveness in Management of Threatened Preterm Labor Between Cervical Length-based Approach and Conventional Approach: A Randomized Control Trial

Status

Withdrawn

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04301388

Enrollment

Registered

2020-03-10

Start date

2020-01-22

Completion date

2021-01-31

Last updated

2021-08-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Preterm Delivery Within 7 Day After Admission

Brief summary

To compare the effectiveness of treatment of threatened preterm labor between transvaginal cervical length-based approach and conventional approach (Per vaginal examination)

Interventions

PROCEDURETransvaginal ultrasound

Transvaginal ultrasound to measure cervical length if persist regular uterine contraction

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

NONE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Pregnant with symptoms of threatened preterm labor which refer to regular uterine contractions at least 1 time in every 10 minutes and persist for 30 minute without cervical dilatation or cervical dilation ≤ 1 cm and \< 80% of effacement. * Age ≥ 18 years * Singleton pregnancy * 24 0/7 - 33 6/7 weeks of gestation * Uneventful antenatal care or low-risk pregnancies

Exclusion criteria

* The definitive diagnosis of true labor * Proceed to the active phase of labor * Age \< 18 years * Multiple pregnancies * \< 24 or ≥ 34 weeks of gestation * Fetal chromosomal or structural abnormalities * Abnormal fetal growth * Abnormal amniotic fluid * Evidence of placenta previa * Significant vaginal bleeding that cannot be ruled out placenta previa * Evidence of rupture of membranes * Evidence of intrauterine infection * Evidence of uterine malformation * Evidence of lethal fetal malformation * Unable to communicate or understand the information of the study

Design outcomes

Primary

Measure	Time frame	Description
Number of cases with delivery within 7 day after admission	From admission to no uterine contraction in 10 minute	In case of threatened preterm labor if detection the progression of labor by transvaginal cervical length, the rate of delivery within 7 days will less or more than conventional group.

Secondary

Measure	Time frame	Description
The number of tocolysis courses, length of hospital stay	From admission to no uterine contraction in 10 minute	In case of tocolytic used for stop labor. The number of medication will be recorded.
The number of steroid courses	From admission to no uterine contraction in 10 minute	In case of stop labor, the course of steroid for promote lung maturity is recorded.

Countries

Thailand

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026