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ESP Block vs. Traditional Pain Management for ERAS

Erector Spinae Plane Block Versus Traditional Pain Management for Enhanced Recovery After Surgery

Status
UNKNOWN
Phases
Phase 3
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04299035
Enrollment
300
Registered
2020-03-06
Start date
2020-03-05
Completion date
2021-09-05
Last updated
2020-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Pain

Keywords

Postoperative pain, Erector spinae plane block

Brief summary

Patients undergoing thoracotomy, thoracoscopy or other surgical procedures involving the integrity of the chest wall are always in a special point of interest of both surgical and anesthesiological specialities. Most of the patients will describe the pain after thoracic surgery as severe. It might lead to a number of serious complications: respiratory failure due to splinting; inability to clear secretions by effective coughing, with resulting pneumonia; and turning into a chronic pain: the post-thoracotomy pain syndrome. Traditional pain management in these groups of patients - such as opiate treatment, thoracic epidural analgesia, and non-opioid drugs - may have serious side effects. Large doses of opiates suppress the cough reflex and lead to respiratory depression with subsequent re-intubation and re-ventilation. Thoracic epidural analgesia, though being considered paramount among other analgesic options, requires a significant clinical experience. Still, it might be insufficient for satisfactory pain control and even complicated with pneumothorax, total spinal anaesthesia and inadvertent intravascular injection. Non-steroidal anti-inflammatory drugs (NSAIDs) and Tramadol are weak analgesics inadequate for severe pain control and might be responsible for gastrointestinal bleeding. We suggest performing erector spinae plane block for intraoperative and postoperative pain management due to the ease of use and better analgesic effect. What remains is hard proof for the clinical efficacy and safety of this block, followed by a demonstration of the uptake of it in the hands of non-regional anaesthetists.

Interventions

PROCEDUREErector spinae plane block

Erector spinae plane block

Sponsors

Soroka University Medical Center
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* all consecutive adult patients who undergo thoracic, spinal or abdominal surgery in Soroka Medical Center, and agree to participate in the study, older than 18 years, who meet criteria of ASA physical status I-II-III-IV class.

Exclusion criteria

* Unconscious or mentally incompetent patients or those who refuse to participate in the study.

Design outcomes

Primary

MeasureTime frameDescription
Visual Analog Pain Score3 daysReported immediate postoperative VAS score, up to 3rd day
Total pain med consumption in the PACU3 hoursTotal Morphine, NSAIDs and Tramadol amount (mg) in the PACU
Length of stay in the PACU24 hoursLength of stay in postoperative care room

Secondary

MeasureTime frameDescription
Length of hospital stay30 daysLength of hospital stay
Chronic pain development6 monthsRate of chronic pain at 3 and 6 months after surgery

Countries

Israel

Contacts

Primary ContactDmitry Natanel, MD
nataneld@bgu.ac.il+972533360451
Backup ContactMichael Dubilet, MD
michaeldu@clalit.org.il

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026