Dental Caries, Oxidative Stress, Passive Smoking
Conditions
Brief summary
The purpose of the present study was to determine the effect of passive smoking on oxidative stress and dental caries in children.A total of 180 children were included to the study as follows; 90 children exposed to passive smoking, and 90 children in the control group (unexposed controls). Also demographic data were recorded (age, gender, parental education levels, child's tooth-brushing habit and child's daily dietary sugar exposure, family income). Dental examination of children were performed and caries prevalence of the patients were recorded. Unstimulated saliva samples were collected from children. Saliva 'cotinine levels' and oxidative stress markers 'total antioxidant status' (TAS), and' total oxidant status' (TOS) were evaluated by using Enzyme-linked immunosorbent assay (ELISA). The obtained data parameters of the two groups were evaluated and comparison was performed.
Interventions
DIAGNOSTIC_TESTtaking saliva samples to determine oxidative stress markers TAS and TOS
Sponsors
Kırıkkale University
Merve Erkmen Almaz
Study design
Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
6 Years to 12 Years
Healthy volunteers
Yes
Inclusion criteria
-Systemically healthy children
Exclusion criteria
* Uncooperative children * The presence of orthodontic/intraoral appliance * Any disease or condition known to affect oxidative stress
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| determining oxidative stress marker in saliva: TAS | 1 day (once after the dental examination)] | Unstimulated saliva samples were collected from children. |
| determining oxidative stress marker in saliva: TOS | 1 day (once after the dental examination) | Unstimulated saliva samples were collected from children. |
| determining caries prevalence | 1 day (once for dental examination) | Children were examined to determine caries prevalence. |
Outcome results
None listed