Persistent Ductus Arteriosus, Pre-Term
Conditions
Keywords
near-infrared spectroscopy, preterm infant, echocardiography
Brief summary
This study evaluates the brain and renal oxygenation using near infrared spectroscopy in preterm infants with persistent ductus arteriosus
Detailed description
Patent ductus arteriosus (PDA) is common in preterm infants. In the presence of a large PDA, significant systemic to pulmonary shunting occurs, which may result in pulmonary hyperperfusion and systemic hypoperfusion. The evidence on PDA effect on brain and renal tissue oxygenation, measured by Near Infrared Spectroscopy is still controversial. This study aims to evaluate the brain and renal oxygenation using near infrared spectroscopy (NONIN SenSmart model X-100) in 3 groups of preterm infants: 1) closed ductus arteriosus, 2) persistent ductus arteriosus, 3) hemodynamicaly significant ductus arteriosus.
Interventions
DEVICENONIN SenSmart model X-100 near- infrared spectrometer
for to measure cerebral (cSO2) and renal (rSO2 ) regional tissue oxygen saturation on the day after echocardiography was done. The sensors were placed on the right/left forehead and the right/left lateral posterior flank
Sponsors
Vilnius University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
22 Weeks to 32 Weeks
Healthy volunteers
No
Inclusion criteria
* preterm infants with gestation age of \< 32 weeks * birth weight \< 1500g * \> 72 hours of age.
Exclusion criteria
* cardiovascular, renal, cerebral congenital defects, * confirmed sepsis, * no parental consent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Differences of the mean values of regional oxygenation of the brain and renal | from Day 4 of live up to 36 weeks | Cerebral and renal regional tissue oxygen saturation monitoring on the day after echocardiography was done |
Countries
Lithuania
Outcome results
None listed