Three-dimensional (3D) Rectal Water Contrast Transvaginal Ultrasonography Versus Computed Colonography in the Diagnosis of Rectosigmoid Endometriosis

Three-dimensional Rectal Water Contrast Transvaginal Ultrasonography Versus Computed Colonography in the Diagnosis of Rectosigmoid Endometriosis

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04295343

Enrollment

Registered

2020-03-04

Start date

2017-03-01

Completion date

2020-02-01

Last updated

2020-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Endometriosis, Rectum, Endometriosis, Sigmoid

Keywords

Rectosigmoid endometriosis

Brief summary

Rectosigmoid involvement by endometriosis causes intestinal symptoms such as constipation, diarrhea, and dyschezia. A non-invasive diagnosis of bowel endometriosis is relevant to provide the patients information on the potential hormonal or surgical treatments. The objective of the current study was to compare the performance of three-dimensional rectal water contrast transvaginal ultrasonography (3D-RWC-TVS) and computed colonography (CTC) in predicting the presence and characteristics of rectosigmoid endometriosis.

Interventions

DIAGNOSTIC_TESTThree-dimensional (3D) rectal water contrast transvaginal ultrasonography

Rectal water contrast transvaginal ultrasonography is based on the distention of rectosigmoid with saline solution. Three-dimensional reconstructions convert standard 2D grayscale ultrasound acquisitions into a volumetric dataset.

DIAGNOSTIC_TESTComputed colonography

Computed colonography or virtual colonoscopy uses special x-ray equipment to examine the large intestine. During the exam, a small tube is inserted a short distance into the rectum to allow for inflation with gas while computed tomographic images of the colon and the rectum are taken.

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

\- pain and intestinal symptoms suggestive of rectosigmoid endometriosis

Exclusion criteria

* previous surgical diagnosis of intestinal endometriosis * previous radiological diagnosis of intestinal endometriosis (based on Magnetic Resonance or double-contrast barium enema * history of colorectal surgery (except appendectomy) * contraindications to bowel preparation or computed colonography (such as non-- compliant patients and rectal malformations) * previous bilateral ovariectomy * psychiatric disorders

Design outcomes

Primary

Measure	Time frame	Description
To compare the accuracy of 3D-RWC-TVS and CTC in the diagnosis of rectosigmoid endometriosis.	At maximum 6 months before laparoscopic surgical approach	The results of imaging will be compared with surgical and histological findings.

Secondary

Measure	Time frame	Description
To compare the precision of 3D-RWC-TVS and CTC in estimating the length (mid-sagittal diameter) of the rectosigmoid endometriotic nodules	At maximum 6 months before laparoscopic surgical approach	The results of imaging will be compared with surgical and histological findings.
To compare the accuracy of 3D-RWC-TVS and CTC in the diagnosis of multifocal rectosigmoid endometriosis.	At maximum 6 months before laparoscopic surgical approach	The results of imaging will be compared with surgical and histological findings.
To compare the precision of 3D-RWC-TVS and CTC in estimating and the distance between the lower margin of the rectosigmoid endometriotic nodules and the anal verge	At maximum 6 months before laparoscopic surgical approach	The results of imaging will be compared with surgical and histological findings.

Countries

Italy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026