Comparing Buccal Infiltration and Inferior Alveolar Nerve Block for Extraction of Mandibular Teeth

Effectiveness of Buccal Infiltration and Inferior Alveolar Nerve Block With Articaine for Extraction of Mandibular Teeth- A Randomized Clinical Trial

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04294745

Enrollment

Registered

2020-03-04

Start date

2019-02-01

Completion date

2020-01-30

Last updated

2023-10-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Buccal Infiltration Inferior Alveolar Nerve Block Articaine

Keywords

Buccal infiltration inferior alveolar nerve block Articaine

Brief summary

This study compares the effectiveness of two techniques of local anesthesia in the extraction of mandibular teeth. One group received inferior alveolar nerve block and the other group received buccal infiltration of 4% Articaine

Detailed description

Inferior alveolar nerve block is the commonly used local anesthetic injection technique for extraction of mandibular teeth. Buccal infiltration technique alone is considered to be ineffective in treating mandibular teeth due to the thickness of buccal cortical plate. However, buccal infiltration, if provided with an agent with higher penetration capability, may be used instead of Inferior alveolar nerve block. Articaine, due to its thiophene ring, has higher liposolubility and bony diffusion than any other agent. This study compares the effectiveness of inferior alveolar nerve block and buccal infiltration using 4% Articaine in the extraction of mandibular teeth

Interventions

PROCEDUREBuccal infiltration

Injection of local anaesthetic parallel to the Long axis of the tooth in the depth of buccal sulcus

PROCEDUREInferior alveolar nerve block

Standard technique of mandibular nerve block

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Yes

Inclusion criteria

* Mandibular teeth * grossly decayed teeth * root stumps * therapeutic extractions * American society of anesthesiologist classification I & II patients

Exclusion criteria

* patients allergic to local anesthesia * infected teeth * grade 2 and grade 3 mobile teeth * patients already taking medications which influences the anaesthetic assessment

Design outcomes

Primary

Measure	Time frame	Description
Pain during injection using a visual analogue scale measuring 10 cm with 0 depicting no pain and 10 depicting severe pain	During injection	VAS scale is a validated scale measuring pain with possible score range from 0 (no pain) to 10 (severe pain).
Pain during extraction using a visual analogue scale measuring 10 cm with 0 depicting no pain and 10 depicting severe pain	During extraction	VAS scale is a validated scale measuring pain with possible score range from 0 (no pain) to 10 (severe pain).
Requirement of rescue injection	During extraction	whether a recue injection was given or not

Countries

Malaysia

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026