Anastomotic Leak, Gastric Cancer, Gastroscopy, Surgery, Testing, Reality
Conditions
Keywords
Anastomotic leakage, Gastric cancer, Leakage testing, Total gastrectomy, Gastroscopy
Brief summary
Anastomotic leak after radical gastrectomy is a serious complication. Intraoperative leak testing was often used to assess the integrity of the anastomosis. However, the reliability, clinical benefits and safety of intraoperative leak testing are controversial. Our aim is to evaluate the effect and safety of intraoperative leak testing, and to compare the surgical complications of patients in intraoperative leak testing group with patients in non-intraoperative leak testing group.
Detailed description
Anastomotic leak after radical gastrectomy is a serious complication. Intraoperative leak testing was often used to assess the integrity of the anastomosis. However, the reliability, clinical benefits and safety of intraoperative leak testing are controversial. Our aim is to evaluate the effect and safety of intraoperative leak testing, and to compare the surgical complications of patients in intraoperative leak testing group with patients in non-intraoperative leak testing group. patients underwent total gastrectomy for gastric cancer, with esophagojejunostomy reconstruction.
Interventions
PROCEDUREIntroperative leak testing
After anastomosis was completed. We test the integrity of anastomosis intraoperatively.
Sponsors
Nanchong Central Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to 85 Years
Healthy volunteers
No
Inclusion criteria
1. resectable gastric carcinoma according to the eighth edition of the TNM (clinical stages I-III). 2. Eastern Cooperative Oncology Group performance status of 0 or 1. 3. American Society of Anesthesiologists class of I-III.
Exclusion criteria
1. Patients had distant metastasis. 2. presence of obvious contraindications to surgery (e.g., liver and/or kidney function abnormalities). 3. any participation in another clinical trial within the past 6 months. 4. Previous chemotherapy or radiation therapy for any other malignancies. 5. past history of gastric resection, gastric cancer-related complications, other malignancy diagnosed within the previous 5 years,
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Anastomotic leakage | 2 months | all patients underwent upper gastrointestinal radiography after surgery for detecting the integrity of anastomosis. X-ray to detect the integrity of the anastomosis |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Postoperative surgical complications | 3 months | Any surgical complication that occured postoperatively |
Countries
China
Outcome results
None listed