Skip to content

The Effects of Red Spinach Extract Supplementation on Isometric Strength, Resistance Exercise and Cognitive Performance

The Effects of Red Spinach Extract Supplementation on Isometric Strength, Resistance Exercise and Cognitive Performance.

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04292106
Enrollment
11
Registered
2020-03-02
Start date
2019-09-26
Completion date
2020-03-30
Last updated
2022-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sports

Brief summary

Red Spinach is a natural food which is a rich source of nitrates, which are beneficial in hemodynamics, cardiovascular function, and have natural hypotensive and antianginal effects. Red spinach extract has been shown to be beneficial in exercise performance, albeit mostly in aerobic exercise. In a previous study in our lab, we found that dietary nitrate consumption resulted in significantly greater isometric force production in teenage males. However, currently there is little know regarding the effects of dietary nitrate supplementation on isometric strength, resistance exercise and cognitive performance.

Detailed description

This research study is designed to measure the effects of red spinach extract (RSE) on markers of physical and cognitive performance during and following anaerobic exercise.

Interventions

DIETARY_SUPPLEMENTRed Spinach Extract (RSE)

Oral capsules containing 2g of Red Spinach Extract will be consumed daily for 7 days

DIETARY_SUPPLEMENTPlacebo

Oral placebo capsules will be taken consisting of maltodrextrin daily for 7 days

Sponsors

Lipscomb University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender
MALE
Age
18 Years to 34 Years
Healthy volunteers
Yes

Inclusion criteria

* 18-34 years old Participants must have at least 1 year of resistance training experience. * Free of any physical limitations, medications, and supplements that may affect performance, as determined by a health and activity questionnaire. * Are free of musculoskeletal injuries * Are not taking medications that may interfere with study measurements

Exclusion criteria

* Participants that cannot take either the RSE or placebo supplement will be excluded, as this will be a double-blind study. * Furthermore, participants that cannot participate in pre- and post-research testing, and/or those that cannot commit to regular training sessions will be excluded. * Inability to perform physical exercise (determined by health and activity questionnaire) * Taking any other nutritional supplement or performance enhancing drug. * Any chronic illness that causes continuous medical care

Design outcomes

Primary

MeasureTime frameDescription
Bench Press Repetitions to FatiugeThrough study completion, during both treatments (~4 weeks)Number of repetitions completed in each set during the acute exercise bout will be recorded and analyzed
Bench Press PowerThrough study completion, during both treatments (~4 weeks)Power during bench press repetitions will be measured via a linear transducer.
Isometric Mid-thigh pull (IMTP) Peak ForceThrough study completion, during both treatments (~4 weeks)Peak Force will be measured via dual force plates during a full-body isometric strength test.
Isometric Mid-thigh pull (IMTP) Rate of Force DevelopmentThrough study completion, during both treatments (~4 weeks)Rate of Force development will be measured via dual force plates during a full-body isometric strength test.

Secondary

MeasureTime frameDescription
Estimated Muscle Blood Flow via Near-infrared Spectroscopy (NIRS)Through study completion, during both treatments (~4 weeks)Measures of muscle oxygenation of the anterior deltoid will be estimated using a NIRS Device.
Cognitive Performance via Stroop TestThrough study completion, during both treatments (~4 weeks)The Stroop Color and Word Test (SCWT) is a neuropsychological test used to assess cognitive performance. This will be administered before and after the fatiguing bench press protocol

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026