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Development and Validation for Predicting Inadequate Bowel Preparation

Development and Validation for Predicting Inadequate Bowel Preparation Before Colonoscopy in Patients

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04290715
Enrollment
1644
Registered
2020-03-02
Start date
2020-01-01
Completion date
2021-04-30
Last updated
2021-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cathartics, Colonoscopy, Polyethylene Glycol

Brief summary

High-quality colonoscopy is considered the gold standard for the detection and prevention of colorectal cancer, and its efficacy is predicated on optimal colon cleansing.However, about 18%-35% of patients were still reported to suffer inadequate bowel preparation. Although several predictive models exist, the current guideline indicates that there is insufficient evidence to recommend the use of a predictive model for clinical practice.

Interventions

OTHERno intervention

no intervention

Sponsors

Ningbo No. 1 Hospital
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* patients undergoing colonoscopy. * patients older than 18 years.

Exclusion criteria

* Emergency colonoscopy. * Have a serious medical condition, such as heart failure, acute liver failure, severe kidney disease (dialysis or predialysis patients) or New York heart association class iii-iv. * Pregnant or breastfeeding. * No bowel preparation or poor compliance (no bowel preparation as instructed or laxatives \< 90% of prescribed dose). * Refuse to sign informed consent. * The patient was rescheduled after the previous colonoscopy due to insufficient bowel preparation. * Temporarily change to colonoscopy for other reasons. * Incomplete colonoscopy due to insufficient parenteral preparation. * Lack of complete data.

Design outcomes

Primary

MeasureTime frameDescription
quality of bowel preparationA colonoscopy procedureThe OBPS is a validated scoring system with scores between 0 and 14, where 0 is the best score. The score comprises a sub score 0-4 for each colon segment: right, transverse and rectosigmoid colon. In addition, a score 0-2 is added to indicate the total amount of luminal fluid. For all participants, OBPS score will be used when the colonscopy is inserting.

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026