Speech Perception
Conditions
Brief summary
Understanding speech is one of the most important functions of the human brain. We use information from both the auditory modality (the voice the of person we are talking to) and the visual modality (the facial movements of the person we are talking to) to understand speech. We will use intracranial encephalography to study the organization and operation of the brain during audiovisual speech perception.
Interventions
OTHERMeasurement of brain activity using electrodes.
We will present audiovisual speech and record neural responses.
Sponsors
University of Pennsylvania
Columbia University
Baylor College of Medicine
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
21 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* must be undergoing neurosurgery for the treatment of a brain disorder
Exclusion criteria
* must have corrected-to-normal vision and hearing
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Measurement of neural activity | During the procedure. | The name of the measurement is the broadband high-frequency activity (BHA) in the brain in response to audiovisual speech. The unit of measure is % increase in power from pre-stimulus baseline. The name of the measurement tool is intracranial EEG, recordings of the raw voltage signal from each electrode implanted in the brain. The voltage-by-time signal will be converted to spectral space using a wavelet transform, and the magnitude of the power between 70 and 150 Hz inclusive in a time window between 0 ms and 500 ms after stimulus onset will be calculated. |
Countries
United States
Outcome results
None listed