Postprandial Hyperglycemia
Conditions
Brief summary
This study investigates whether bread with added galactomannan, a soluble fiber, can reduce the postprandial glucose response in healthy overweight adults.
Detailed description
This single-blind crossover-designed study wants to investigate the postprandial effect of functional bread in healthy overweight adults. Therefore, four types of bread, consumed by the participants, have added galactomannan in different amounts and viscosities, and one bread is the control bread. The participants arrive after an overnight fast and before the consumption of bread, a fasting blood sample is taken. After the ingestion, blood samples are taken at specific times. The area under the curve of the postprandial glucose is expected to differ between the functional breads.
Interventions
DIETARY_SUPPLEMENTFunctional bread
Postprandial effects of bread containing galactomannan
Sponsors
University of Bergen
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
SINGLE (Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
* healthy, overweight adults (BMI between 25 and 30 kg/m2)
Exclusion criteria
* Known diagnosis of diabetes mellitus type 2 * HbA1c at screening ≥ 48 mmol/mol * Other chronic diseases (heart disease, cancer) within the last 3 years * Pregnancy and lactation * Known drug or alcohol abuse * Unwilling to follow the study requirements
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| area under the curve of postprandial glucose | 180 minutes |
Secondary
| Measure | Time frame |
|---|---|
| area under the curve postprandial insulin | 180 minutes |
Countries
Norway
Outcome results
None listed