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Associated Disorders of Locomotion and Postural Control of Axial Segments in Cerebral Palsy

Associated Disorders of Locomotion and Postural Control of Axial Segments in Cerebral Palsy

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04287673
Enrollment
17
Registered
2020-02-27
Start date
2016-12-20
Completion date
2019-11-30
Last updated
2024-07-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cerebral Palsy, Spastic

Keywords

Trunk control, Postural Control, Cerebral Palsy, Rehabilitation, Axial segments

Brief summary

Gait abnormalities, which occur in Cerebral Palsy (CP), are characterized usually by a toe-to-floor or a plantar-to-floor initial contact (equinus gait), followed by an early braking of the tibia's forward progression (during ankle dorsiflexion). This causes consequently a trunk deceleration. Moreover, children with CP have difficulties to stabilize the trunk and the head in the space, and that could have impact on gait. If equinus gait is often attributed to the triceps surae spasticity, recent works suggest rather that this early braking of the dorsiflexion could be a motor adaptation to axial postural control difficulties. This thesis project aims firstly to attest that locomotor disorders are related to these difficulties in the stabilization of the axial body segments in children with CP and, secondly, to show that improving the trunk and head postural control with a specific rehabilitation protocol could reduce the early braking of the dorsiflexion and, consequently, the gait abnormalities observed in CP.

Interventions

OTHERRehabilitation involving strongly the trunk

The Rehabilitation involving strongly the trunk (RIST) leaded by a physiotherapist was based on exercises in different postures performed by the child each day that strongly involve the trunk to cope with balance.

Sponsors

Union de Gestion des Etablissements des Caisses d'Assurance Maladie - Nord Est
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
5 Years to 12 Years
Healthy volunteers
Yes

Inclusion criteria

* Gross Motor Function Classification System I or II * no or minimal contracture of the triceps surae * presence of soleus spasticity

Exclusion criteria

* botulinum toxin injections or surgery in the lower limb respectively in the 6 and 12 months preceding the study * any modification of the physical or orthopaedic therapy within the last two months * minimal hip flexion above 20° in a clinical examination * pain in the lower legs when standing or walking

Design outcomes

Primary

MeasureTime frameDescription
Change of the center of pressure sway area during unstable sitting posturographyChange from baseline to the end of the first 3-months period of rehabilitation and from this latter to the end of the second 3-months period of rehabilitationIn mm²
Change of the peak of trunk's anterior deceleration during the weight acceptance phase of gaitChange from baseline to the end of the first 3-months period of rehabilitation and from this latter to the end of the second 3-months period of rehabilitationIn m/s²
Change of the peak of the center of mass downward deceleration during the weight acceptance phase of gaitChange from baseline to the end of the first 3-months period of rehabilitation and from this latter to the end of the second 3-months period of rehabilitationIn m/s²
Change of the score of the Trunk Control Measurement Scale (TCMS)Change from baseline to the end of the first 3-months period of rehabilitation and from this latter to the end of the second 3-months period of rehabilitationScore from 0 to 58. The higher the score, the better the trunk control.
Change of the center of pressure velicoty during unstable sitting posturographyChange from baseline to the end of the first 3-months period of rehabilitation and from this latter to the end of the second 3-months period of rehabilitationIn mm²/s
Change of the peak of ankle negative power during the weight acceptance phase of gaitChange from baseline to the end of the first 3-months period of rehabilitation and from this latter to the end of the second 3-months period of rehabilitationIn watts per kg.

Secondary

MeasureTime frameDescription
Change of the Dimensionless walking speedChange from baseline to the end of the first 3-months period of rehabilitation and from this latter to the end of the second 3-months period of rehabilitationWalking speed normalized to the length of the lower limb
Change of the dimensionless step widthChange from baseline to the end of the first 3-months period of rehabilitation and from this latter to the end of the second 3-months period of rehabilitationStep width during walking normalized to the width of the pelvis
Change of the center of pressure sway area during quiet standingChange from baseline to the end of the first 3-months period of rehabilitation and from this latter to the end of the second 3-months period of rehabilitationIn mm²
Change of the center of pressure velicoty during quiet standingChange from baseline to the end of the first 3-months period of rehabilitation and from this latter to the end of the second 3-months period of rehabilitationIn mm²/s

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026