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The Effect of Dydrogesterone on Sexual Function in Women With Endometriosis

The Effect of Dydrogesterone on Sexual Function in Women With Endometriosis

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04287205
Enrollment
79
Registered
2020-02-27
Start date
2019-04-20
Completion date
2020-03-03
Last updated
2020-03-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Endometriosis, Sexual Dysfunction

Brief summary

This study aimed to assess the effects of dydrogesterone on sexual function in women with endometriosis using Female Function Sexual Index (FSFI).

Detailed description

Sexual dysfunction is an important outcome for patients with endometriosis. In this study, we compare the fsfi (female sexual function index) questions and the scores before and after dydrogesterone treatment in patients with endometriosis. We aim to measure the effect of dydrogesterone in patients with endometriosis.

Interventions

79 women, aged between 18 and 45 years, who were examined at our tertiary gynecology outpatient clinic between April 2019 and March 2020, with surgically diagnosed endometriosis, were included in this study. They received a treatment with 5 mg dydrogesterone administered orally twice daily for 21 days; from the 5th to 25th day of each menstrual cycle, for a total of 6 months. They were evaluated pre- and posttreatment in terms of their age, parity, and body mass index (BMI). Female Function Sexual Index (FSFI) and visual analogue scale (VAS) scores were recorded pre- and posttreatment

Sponsors

Kanuni Sultan Suleyman Training and Research Hospital
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
FEMALE
Age
18 Years to 45 Years
Healthy volunteers
No

Inclusion criteria

* no history of malignancies, * normal findings at gynecological examinations and transvaginal ultrasonography * normal uterine size, normal cervical smear results, * patients not use any contraception methods in the last 6 months

Exclusion criteria

* with a history of systemic and/or psychiatric diseases, * gynecological pathologies (myoma uteri, endometriosis, uterine anomalies, existing genital infections) * pelvic organ prolapse * pelvic surgeries

Design outcomes

Primary

MeasureTime frameDescription
The Effect of Dydrogesterone on Sexual Function6 monthsIn this study, we compare the fsfi(female sexual function index) questions and the scores before and after dihydrogestreone treatment in patients with endometriosis. We aim to measure the effect of dihydrogesterone in patients with endometriosis.

Secondary

MeasureTime frameDescription
The Effect of Dydrogesterone on Sexual Function in women with endometrioma6 monthsIn this study, we compare the fsfi(female sexual function index) questions and the scores before and after dihydrogestreone treatment in patients with endometriosis. We aim to measure the effect of dihydrogesterone in patients with endometriosis.(with and without endometrioma)

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026