Cardiac Function
Conditions
Brief summary
The main aim of the present investigation is to study cardiac function in different exercise intensities in healthy human subjects. Two techniques will be used: cardiac ultrasound-derived stroke volume measurements and body impedance measurements. 20 healthy men (n=10) and women (n=10) aged 18-45 years will be investigated at rest and during exercise. All study procedures are non-invasive.
Interventions
BEHAVIORALAcute exercise
Acute exercise with different exercise intensities
Sponsors
Turku University Hospital
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 45 Years
Healthy volunteers
Yes
Inclusion criteria
* Age 18-45 * BMI 18-30 * Resting Blood pressure \< 140/90 mmHg * Participation in regular exercise
Exclusion criteria
* Acute illness * Pregnancy * Pace maker * Artificial joint * History of a cardiac event * Insulin or medically treated diabetes * Any chronic disease or condition that could create a hazard to the subject safety, endanger the study procedures or interfere with the interpretation of study results * Abundant use of alcohol * Use of narcotics * Smoking of tobacco or consuming snuff tobacco * Diagnosed depressive or bipolar disorder * Abnormalities in resting ECG (revised by the study physician)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cardiac stroke volume | 1 min |
Secondary
| Measure | Time frame |
|---|---|
| End-diastolic and end-systolic volumes | 1 min |
| Ejection fraction | 1 min |
Countries
Finland
Contacts
Primary ContactIlkka HA Heinonen, PhD
Outcome results
None listed