Echocardiography, Stress, Reference Values
Conditions
Keywords
Echocardiography, Stress, Right ventricle, Mexican population
Brief summary
The echocardiographic indices of the right ventricle function vary significantly with demographic and anthropometric of each population factors and are associated with poor prognosis in several cardiovascular diseases. This study aims to investigate exercise-induced changes in echocardiographic indices of the right ventricle function in healthy volunteers and establish the reference values to the Mexican population.
Interventions
DIAGNOSTIC_TESTStress echocardiography with semi-supine bicycle
The patient is accelerating against a workload that gradually increases at a constant rate, during the exercise the images will be obtained by echocardiography. The patient begins with 25 Watts with increments of 25 Watts every 3 minutes, continuing the exercise until significant electrocardiographic changes occur or the patient starts with symptoms.
Sponsors
National Institute of Medical Sciences and Nutrition, Salvador Zubiran
Miguel Ayala León
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 45 Years
Healthy volunteers
Yes
Inclusion criteria
* Healthy men or women * Age ≥18 years and \< 45. * No history or symptoms of cardiovascular or lung disease * No cardiovascular risk factors, that is, arterial systemic hypertension, smoking, diabetes, dyslipidemia * No ongoing or previous cardio or vasoactive treatment * Normal ECG * Normal physical examination * Able to use the semi-supine exercise bicycle * Able to give informed consent
Exclusion criteria
* Tricuspid regurgitation more than mild * Poor acoustic window. * Professional sports activity * Pregnancy * Obesity (body mass index \[BMI\], ≥30 kg/m2). * No knowledge of serum lipid or glucose levels at any time * Inability to provide consent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Response of diastolic and systolic function of the right ventricle during stress test by echocardiography in a healthy Mexican Cohort | 1 hour | The following variants will be measured by echocardiography during rest and peak exercise Left atrium (LA) * LA volume index Left ventricle (LV) * LV telediastolic diameter * LV telesystolic diameter * LV posterior wall Right atrium (RA) * RA area Right ventricle (RV) * RV basal dimensión * RV mid cavity dimension; * RV longitudinal dimension * Distal, RV outflow tract dimension at the distal or pulmonic valve level * Proximal RV outflow tract dimension at the proximal subvalvular level * Tricuspid annular plane systolic excursion * RV free Wall strain * Inferior cava vein PW Doppler * E wave mitral * A wave mitral * E wave /A wave mitral * E-wave at mitral annulus (cm/s) * E-wave at mitral annulus / A-wave at the mitral annulus * E wave/ E-wave at the mitral annulus * E tricuspid (E) * A tricuspid (A) * E/A * E-wave at the tricuspid annulus * Systolic pulmonary artery pressure * Mean pulmonary artery pressure * Stroke volume * Cardiac output |
Countries
Mexico
Contacts
Primary ContactMiguel Ayala León, MD
Outcome results
None listed