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Factors Influencing Occurrence Of Hilar Biliary Stricture In Case of Bile Duct Injury

Factors Influencing Occurence Of Hight Level of Biliary Stricture Due to Operative Bile Duct Injury

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04286763
Enrollment
53
Registered
2020-02-27
Start date
2010-01-01
Completion date
2018-09-30
Last updated
2020-02-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bile Duct Injury

Keywords

bile duct injury, surgery, laparoscopy, cholecystectomy, Bile duct stricture

Brief summary

The bile duct injury is a complication that occurs mainly after the cholecystectomy. Bile duct stricture is one of complications of this unwitting iatrogenic injury, the outcomes of surgery in this case are worse when the level of the stricture is above the helium. So what are factors influencing the occurrence of this high level bile duct obstruction ?

Detailed description

The objective of this study was to answer a simple question, what are the factors influencing the occurrence of high level -called hilar biliary stricture? To answer this question, a retrospective study was carried out on the files of patients operated for biliary stenosis after operative trauma of the bile ducts in our department over a period from January 2010 to May 2018. Only patients operated in biliary stricture (Grade E Strasberg) was included. A univariate and muntivariate logistic regression analysis was performed to determine the factors influencing the occurrence of hilar stenosis. data entry and analysis was done using SPSS V20.0 software.

Interventions

DIAGNOSTIC_TESTBiliary RMI and CT scan.

For a good appreciation of the anatomy of the biliary lesion, an MRI was systematically performed on all our patients. For a good appreciation of the presence of an associated vascular lesion, a CT-scan was systematically performed on all our patients.

Sponsors

University of Oran 1
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* all cases with biliary stricture following an operative bile duct injury.

Exclusion criteria

* cases of biliary stricture following an non operative bile duct injury (Blind or penetrating abdominal trauma , radiological or endoscopic maneuvers). * cases of biliary stricture following hepatectomy

Design outcomes

Primary

MeasureTime frameDescription
Factors influencing occurrence of hilar stricture (E3,E4,E5)from the date of the surgery that caused the biliary injury to the date of transfer to our structure for treatment. in our series, the period varies from 8 weeks to 10 years after the occurrence of operative bile duct injury during initial surgery.all the variables related to the patient, his disease and the course of the surgical intervention which caused the biliary trauma was recorded.

Countries

Algeria

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026