Two Different Blocks for Postoperative Analgesia in Patients Undergoing Unilateral Total Knee Arthroplasty

Comparison of the Effects of Femoral Nerve Block and Adductor Canal Block on Postoperative Analgesia in Patients Undergoing Unilateral Total Knee Arthroplasty

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04286035

Enrollment

Registered

2020-02-26

Start date

2019-04-02

Completion date

2019-10-01

Last updated

2020-03-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anesthesia, Regional, Knee Replacement, Total, Pain, Postoperative

Keywords

femoral nerve block, adductor canal block, total knee arthroplasty

Brief summary

The frequency of femoral nerve block and adductor canal block for analgesia after TKA(total knee arthroplasty) increases with the use of ultrasonography in regional anesthesia. In this study, we aimed to compare the effects of femoral nerve block and adductor canal block on postoperative analgesia in patients undergoing unilateral knee arthroplasty.

Interventions

DRUGBupivacaine Injection

Femoral nerve block with 20 ml %0.375 bupivacaine

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Caregiver)

Eligibility

Sex/Gender

ALL

Age

55 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* ASA(American Society of Anesthesiologists) Classification I-II * Age: \<55 years * Unilateral total knee arthroplasty

Exclusion criteria

* Does not approve the study * Pregnant * Emergency * ASA III-IV * History of local anesthetic allergy * Infection in the block area * Coagulation disorder * Morbid obesity (body mass index\> 40 kg / m²) * Severe organ failure * Previous neurological deficit * Psychiatric disease * History of chronic pain

Design outcomes

Primary

Measure	Time frame	Description
Tramadol consumption	24 hours after operation	Postoperative tramadol consumption with patient controlled analgesia
VAS(visual analogue scale) score (0-10, 0 is no pain, 10 is the most severe pain)	24 hours after operation	VAS(visual analogue scale) score (0-10, 0 is no pain, 10 is the most severe pain) is less than four is adequate analgesia
Rescue analgesic requirement	24 hours after operation	If VAS(visual analogue scale) score (0-10, 0 is no pain, 10 is the most severe pain) is is four or more, paracetamol 1000 mg is administered

Secondary

Measure	Time frame	Description
Postoperative nausea and vomiting	24 hours after operation	Frequency of postoperative nausea and vomiting

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026