Nd:YAG Laser Hyaloidotomy for Premacular Hemorrhage in Diabetic Eyes

Evaluation of Nd:YAG Laser Hyaloidotomy for Management of Premacular Subhyaloid Hemorrhage in Eyes With Proliferative Diabetic Retinopathy

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04285151

Enrollment

Registered

2020-02-26

Start date

2015-01-31

Completion date

2020-01-31

Last updated

2020-02-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Proliferative Diabetic Retinopathy

Brief summary

Premacular Subhyaloid hemorrhage is a sudden profound loss of vision in eyes with proliferative diabetic retinopathy (PDR). Pars plana vitrectomy is the treatment of choice for premacular hemorrhage in eyes with proliferative changes. Nd:YAG laser hyaloidotomy has been used to evacuate the premacular hemorrhage

Interventions

PROCEDURENd:YAG laser Hyaloidotomy

Using the YAG laser for opening the posterior hyaloid in eyes with premacular hemorrhage, and evacuating the entrapped hemorrhage

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

21 Years to 60 Years

Healthy volunteers

Inclusion criteria

* Eyes with premacular subhyaloid hemorrhage of more than 3 disc diameters, involving the fovea. * Eyes with proliferative diabetic retinopathy

Exclusion criteria

* Dense media opacity (corneal/cataract) * Patients with bleeding tendency or on anti-coagulant drugs

Design outcomes

Primary

Measure	Time frame	Description
Visual acuity improvement	1 week	Testing VA after YAG laser

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026