Effects Exercise Training in Patients With Pituitary Adenoma

Effects of Aerobic Training Combined With Strength Training and Yoga on Biochemical Factors, Physical Performance and Quality of Life in Patients With Pituitary Adenoma

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04284605

Enrollment

Registered

2020-02-26

Start date

2020-05-15

Completion date

2021-10-15

Last updated

2021-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pituitary Adenoma

Brief summary

This study planned to investigate the effects of aerobic training combined with strengthening training and yoga on biochemical factors, physical performance and quality of life in people with pituitary adenoma. The hypotheses are; H1: Aerobic training combined with strengthening training is effective on biochemical factors in people with pituitary adenoma. H2: Aerobic training combined with strengthening training is effective on physical performance in people with pituitary adenoma. H3: Aerobic training combined with strengthening training is effective on quality of life in people with pituitary adenoma. H4: Yoga is effective on biochemical factors in people with pituitary adenoma. H5: Yoga is effective on physical performance in people with pituitary adenoma. H6: Yoga is effective on quality of life in people with pituitary adenoma. H7: Aerobic training combined with strengthening training and yoga is effective on biochemical factors, physical performance and quality of life in people with pituitary adenoma.

Interventions

OTHERAerobic exercise combined with strength training

30 minute aerobic exercise training with warm-up and cool down followed by 30 minute strength training for specific muscles.

OTHERYoga

60 minute yoga intervention including different asanas, breath control and meditation

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

TREATMENT

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Inclusion criteria

* volunteers * macroadenomas * at least 1 hormonal axis affected * Karnofsky Perfomance Scale between 70-100 * 18-65 years * approved by cardiologists

Exclusion criteria

* regular exercise habit * acute pain in many part of the body * additional neurologic condititons * any rheumatological and immunologic conditions

Design outcomes

Primary

Measure	Time frame	Description
Biochemical Factors	6 weeks	Concentrations of IL6, IL1beta, TNFalfa in serum

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026