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Optimum Time for Intravenous Cannulation After Induction With Sevoflurane in Pediatric Patient

Determination Effective Dose 95 (ED95) of Intravenous Cannulation With the Induction of Sevoflurane 8 Vol% in Patients Aged 1-3 Years Using Dixon up and Down Method

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04284579
Enrollment
22
Registered
2020-02-26
Start date
2019-05-27
Completion date
2019-11-30
Last updated
2020-02-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Movement After Intravenous Cannulation

Keywords

child, general anesthesia, induction of anesthesia, sevoflurane, venous cannulation

Brief summary

This study aimed to determinate effective dose 95 (ED95) intravenous cannulation in pediatric patient after induction of sevoflurane 8 vol%

Detailed description

Twenty-two subjects were given informed consent before study enrolled. Anesthesia was induced by 8% sevoflurane with 6 L flow of 100% oxygen. IV cannulation was attempted at 2 min in the first child in each group. The time for cannulation in the next child was stepped up or down by 15 s depending on positive or negative response, respectively, in the previous child. Children were recruited till a minimum of six pairs of failure-success sequence which was obtained in the group. The mean of midpoints of the failure-success sequence was calculated to obtain the time for cannulation in 50% of the group.

Interventions

DEVICEIV cannula

We measure the time duration needed for IV cannulation

Sponsors

Indonesia University
Lead SponsorOTHER

Study design

Intervention model
SEQUENTIAL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
1 Years to 3 Years
Healthy volunteers
Yes

Inclusion criteria

* Age 1-3 year * Physical state ASA I dan II * Parents of patients who agreed to participate and sign informed consent.

Exclusion criteria

* Patients with difficult airway * There's allergic reaction or drug's side effect after induction * There's cardiorespiratory problem such as anaphylactic shock, aritmia, severe hypotension, desaturation before-on-or after induction

Design outcomes

Primary

MeasureTime frameDescription
ED50 in intravenous cannulation after sevoflurane induction2 minutesusing Dixon Up and Down Method

Countries

Indonesia

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026